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Related Episodes for Can caloric restriction supplements mimic fasting? | Dr. Mark Mattson

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What Time-Restricted Eating Adds Beyond Calorie Control

Oct 4, 2024

“Meal timing can affect selected markers in specific settings. In a five-week crossover study of eight men with prediabetes, an early six-hour window improved insulin sensitivity, beta-cell responsiveness, morning blood pressure, oxidative stress, and appetite without weight loss.”

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Why Breakfast Can Support Muscle and Metabolic Health

Dec 19, 2025

“In a controlled five-week crossover trial involving men with prediabetes, an early six-hour eating window with dinner before 3 p.m. improved insulin sensitivity, pancreatic beta-cell responsiveness, blood pressure, oxidative stress, and appetite without causing weight loss.”

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How Supplements May Support Brain Health With Age

Aug 6, 2025

“In this clip from Dr. Rhonda Patrick's appearance on The Tim Ferriss Show, she describes the supplements her parents use and separates a simple nutritional baseline from choices tied to individual health needs.”

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How to Fill Common Nutrient Gaps

Jul 17, 2025

“She highlights its roles in brain health and homocysteine metabolism. Product quality matters for omega-3 supplements because these fats oxidize readily; she favors products with third-party testing for oxidation and labeled EPA and DHA content, with algal oil as a vegan option.”

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Aliquot #100: Optimizing for a Healthy Pregnancy & Early Childhood

Jan 8, 2024

“Dr. Rhonda Patrick spent many months researching and learning about the myriad factors that would influence her child's development, and she has continued to do so as her son has grown – and as new research has become available.”

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Duration: 57m 40s
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Aliquot #101: How Omega-3s Combat Age-Related Muscle Atrophy

Jan 30, 2024

“Rebuilding muscle relies on proper nutrition and exercise, but aging reduces the body's response to both. Extended periods of inactivity, such as post-surgery or during illness, can rapidly deplete muscle mass, especially in older people, potentially pushing them into a "catabolic crisis."”

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Duration: 31m 37s
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Aliquot #109: Reducing ApoB with diet, drugs, and supplements

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“However, dietary strategies, pharmaceuticals, and some supplements may reduce ApoB levels. In this Aliquot – a follow-up to Aliquot #81 – Dr. Peter Attia and I talk about some of the nutritional, pharmaceutical, and supplemental approaches to reduce ApoB.”

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Duration: 1h 9m 11s
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Aliquot #114: Supplements & Diet Strategies to Boost Mitochondrial Function

Oct 28, 2024

“Mitochondria are best known for their energy-producing roles, but they also help regulate cellular metabolism, signaling, and apoptosis (programmed cell death). As a result, mitochondrial health is intrinsically linked to overall health.”

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Aliquot #120: How the Experts Build Muscle Mass

Jan 21, 2025

“Part 3 of this series focuses on maximizing and maintaining muscle mass—an essential part of long-term health and fitness—with insights from exercise physiologist and nutrition expert Dr. Luc van Loon and exercise scientist Layne Norton.”

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Aliquot #123: Diet & Lifestyle Strategies for Optimizing Eye Health

Mar 10, 2025

“Maintaining healthy vision is more than just correcting eyesight—it's about nourishing your eyes, practicing good habits, and exploring cutting-edge tools and techniques to protect and enhance your vision. In this Aliquot, you'll hear expert insights from Drs.”

aliquot exercise diet eyes
Duration: 20m 4s
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