Related Episodes for Dr. Eran Elinav: Microbiome Insights into Personalized Response to Diet, Obesity, and Leaky Gut

“Other hormetic responses to cold exposure include increased production of PGC1-alpha, a protein that promotes mitochondrial biogenesis, the production of new, healthy mitochondria, and the activation of brown fat – a phenomenon once thought to occur only in newborns, but now known to occur in adults, especially after cold exposure.”

“Perhaps the most clear-cut examples of cryotherapy’s beneficial effects are observed in the brain, where levels of the hormone and neurotransmitter norepinephrine – responsible for vigilance, attention, focus, and positive mood – increase markedly when the body is exposed to extreme cold.”

“However, the term "fasting" can comprise a variety of subtypes. Intermittent fasting, a term lacking specificity, usually refers to interventions such as alternate-day fasting, fasting one day per week, or a five:two eating pattern (fasting for two days per week).”

“For example, while vitamin C acts primarily as an antioxidant at physiological concentrations of approximately 50 micromoles per liter, pharmacologic doses of intravenous vitamin C greater than 1 gram generate hydrogen peroxide, a type of reactive oxygen species produced by neutrophils to destroy pathogens such as viruses.”

“Dr. Rhonda Patrick – who wears a continuous glucose monitor – has found that her post-smoothie blood glucose levels are markedly lower when her smoothie contains moringa powder. In this clip, Dr. Rhonda Patrick shares anecdotal evidence that moringa reduces blood glucose levels.”

“While some forms of Parkinson's disease are genetic, most cases involve a complex interaction between genetic and environmental risk factors. In the early 1980s, intravenous drug users inadvertently injected a contaminated drug and developed parkinsonian symptoms overnight.”

“Conventional health advice, such as healthy eating, physical activity, and education level are linked with slowed epigenetic aging, albeit weakly, and obesity, sleep deprivation, and smoking are linked with accelerated epigenetic aging.”

“Patients assigned to supervised exercise during neoadjuvant chemoradiation, followed by continued activity before surgery, were more likely to achieve a complete or near-complete pathological response than those receiving usual care.”

“A larger randomized-trial meta-analysis also found modest average reductions in BMI, waist circumference, and body-fat percentage, although protocols and populations varied. These averages do not mean that HIIT alone guarantees fat loss.”

“The physical activity guidelines and estimates on how much activity we need are heavily based on self-reported activity, which is useful but imperfect: people remember going for a run, but they forget the short, intense bursts in daily life like sprinting up stairs, chasing kids, and running to catch a bus.”