Ranked by shared topics, with one result from each original episode.
Episode
“Tools, companies, and resources mentioned OpenAI - AI research and deployment company behind widely used GPT systems and developer tools; its science case study describes GPT-5 helping Unutmaz's lab resolve a long-standing immunology question.”
Episode
“Moreover, taking mega doses (i.e. 400 IU/day) of alpha tocopherol has the unintended side-effect of actually depleting tissue levels of another important form of vitamin E that plays an anti-inflammatory role, known as gamma tocopherol.”
Episode
“Rather, they fall on a spectrum, ranging from a five-to-one ratio of fats to protein and carbs (typically used in clinical settings) to a more liberalized one-to-one ratio, a type of low glycemic index therapy (commonly referred to as "modified Atkins") that might meet the needs of most healthy people.”
Clip
“Aging in tumor tissue is markedly accelerated, however – an indicator of the perturbed metabolic and growth processes observed in cancer. In this clip, Dr. Steve Horvath discusses correlations between epigenetic aging and age-related chronic diseases.”
Clip
“Patients assigned to supervised exercise during neoadjuvant chemoradiation, followed by continued activity before surgery, were more likely to achieve a complete or near-complete pathological response than those receiving usual care.”
Clip
“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”
Clip
“Dr. Patrick also describes a proposed anti-metastatic mechanism: faster blood flow during vigorous exercise increases shear forces on circulating tumor cells, the cells that have left a primary tumor and entered the bloodstream.”
Clip
“In this excerpt from Dr. Rhonda Patrick’s A4M LongevityFest 2023 keynote, she reviews a randomized trial in sedentary middle-aged adults. Two years of progressive, supervised aerobic training increased VO2 max and reduced left-ventricular stiffness.”
Clip
“In this clip, Drs. Levine and Patrick discuss genetic and environmental factors that can accelerate or slow epigenetic aging. Dr. Levine also discusses the aging clock she created and how it can be used, along with other biomarkers, to determine an individual's rate of aging.”
Clip
“Dr. Patrick explains some of the early evidence that suggests the value prolonged fasting (48+ hours) may have from the standpoint of tissue rejuvenation and healthspan maintenance, as well as relevance for other more specific conditions.”