Related Episodes for Weight loss and reversing metabolic syndrome may slow epigenetic aging | Steve Horvath

“Berberine is a plant-derived compound that may be beneficial for treating a wide range of chronic health conditions associated with obesity, such as hypertension, dyslipidemia, and type 2 diabetes, among others.”

Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...

“However, combining fasting with resistance training can stimulate muscle growth. In this Aliquot, Dr. Rhonda Patrick discusses time-restricted eating, fasting, and muscle preservation, highlighting key differences and offering recommendations for specific groups.”

“Time-restricted eating involves consuming meals within a specific daily time window. However, choosing the optimal time frame for that window is influenced by many factors, the most important of which is circadian rhythmicity, which alters our body's metabolic responses to food.”

“Early biomarkers of vascular dysfunction, such as soluble platelet-derived growth factor receptor-beta (sPDGFR-β), can help identify individuals at risk for developing Alzheimer's disease. These biomarkers are being validated on high-throughput platforms for large-scale testing.”

“While sanitation and clean drinking water are critical to survival, the over sterilization of our environment may play a role in modulating the human immune system. In this clip, Dr. Charles Raison highlights how ancient practices such as heat exposure, long-distance running, and fasting may promote well-being in the modern world.”

“However, the ability to translate data from non-human animals to humans can be limited and the use of laboratory animals can raise ethical concerns. In this clip, Dr. George Church describes the pros and cons of animal research and how we could move beyond its use with advanced technologies.”

“The mechanisms that drive the effects of sauna bathing include activation of heat shock proteins and pro- and anti-inflammatory cytokines; decreased blood pressure and arterial stiffness; and multiple improvements in cardiovascular function.”

“Approximately 25 percent of people living in the United States carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

“Microbial responses to individual components of a person's diet may influence host health. Food ingredients, such as artificial sweeteners and dietary emulsifiers, are typically thought to be inert, however, recent evidence suggests they impact gut microbes, ultimately influencing human health.”