Related Episodes for Drs. Bill Harris and Rhonda Patrick comment on omega-3 prostate cancer study SELECT trial

Dan Pardi: Ph.D. candidate studying sleep neurobiology at Stanford and University of Leiden, co-founder of Dan’s Plan online wellness company.

“Dr. Candow explains why a hormone change within the physiological range cannot by itself establish a hair effect. A later 12-week randomized trial directly measured hormones and hair-follicle outcomes in resistance-trained men taking five grams of creatine per day.”

“Tools, companies, and resources mentioned OpenAI - AI research and deployment company behind widely used GPT systems and developer tools; its science case study describes GPT-5 helping Unutmaz's lab resolve a long-standing immunology question.”

“Moreover, taking mega doses (i.e. 400 IU/day) of alpha tocopherol has the unintended side-effect of actually depleting tissue levels of another important form of vitamin E that plays an anti-inflammatory role, known as gamma tocopherol.”

“Rather, they fall on a spectrum, ranging from a five-to-one ratio of fats to protein and carbs (typically used in clinical settings) to a more liberalized one-to-one ratio, a type of low glycemic index therapy (commonly referred to as "modified Atkins") that might meet the needs of most healthy people.”

“Patients assigned to supervised exercise during neoadjuvant chemoradiation, followed by continued activity before surgery, were more likely to achieve a complete or near-complete pathological response than those receiving usual care.”

“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”

“Dr. Patrick also describes a proposed anti-metastatic mechanism: faster blood flow during vigorous exercise increases shear forces on circulating tumor cells, the cells that have left a primary tumor and entered the bloodstream.”

“Dr. Patrick explains some of the early evidence that suggests the value prolonged fasting (48+ hours) may have from the standpoint of tissue rejuvenation and healthspan maintenance, as well as relevance for other more specific conditions.”

“Gaining FDA approval of psilocybin under these conditions is problematic, however, due to the negative connotations associated with the compound's use and the potential for harm when used in vulnerable populations.”