Related Episodes for The Hidden Connection Between Sleep and Dementia

“Circulating LPS can also bind to lipoproteins, facilitating their absorption in the liver during LDL recycling, effectively removing LPS from circulation and lowering systemic inflammation – a phenomenon demonstrated mechanistically with statins that increase lipoprotein recycling by increasing LDL receptors.”

Many of the anabolic effects of growth hormone are thought to be mediated by insulin-like growth factor-1, or IGF-1 (https://www.ncbi.nlm.nih.gov/pubmed/18500379), which is synthesized primarily in the liver but also in skeletal muscle in response to growth hormone.

“More importantly, however, these effects were sustained – even after several months – demonstrating that sulforaphane did not exhaust the body's capacity to protect itself from environmental threats and suggesting that regular consumption of sulforaphane in foods or dietary supplements provides a kind of nutritional "seatbelt" that protects against future toxic exposures.”

“Few topics come up in their discussion where Dr. Fahey doesn't have an anecdote about a study he was involved in, or, in some cases, "tribal knowledge" that may not even be published but is nonetheless interesting and an important part of the story that is unique to his particular vantage point.”

Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.

“Study. 01:43:00 - High animal protein intake was only positively associated with cardiovascular mortality among individuals with at least one unhealthy lifestyle risk factor, such as obesity or sedentary lifestyle. Study.”

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

“Finally, choline is also a precursor for phosphatidylcholine, the major component of all cell membranes, which affects the structure, permeability and function of cells and is particularly important in neurons since it plays a role in general neurotransmission.”

“Dr. Patrick recommends bounded quality checks such as GMP manufacturing and independent testing; she notes that some tested products were below their stated heavy-metal limits, not that lion’s mane products are uniformly contaminated.”

“A preliminary study shows atrophy in olfactory brain regions and areas responsible for learning and memory, after COVID-19 illness, even in those with mild cases. Converging evidence suggests that the long-term impacts of SARS-CoV-2 infection are unknown.”