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This podcast is about one of the most important biological pathways you could possibly take the time to learn about: the NRF2 pathway.

MedCram co-founder Kyle Allred discusses sauna's exercise mimetic, anti-inflammatory, mood-elevating, and detoxifying properties in this episode.

A modest change on the "micronutrient smoothie" that also talks about the beneficial compounds that don't qualify as micronutrients.

Dr. Valter Longo discusses the role of fasting and the fasting-mimicking diet in longevity, cancer & multiple sclerosis.

Dr. Satchin Panda discusses the roles that fasting, time-restricted eating, and circadian rhythms play in human health.

Dr. Brad Schoenfeld studies the importance of resistance exercise in maintaining muscle mass.

Dr. David Sinclair discusses the mechanisms that drive human aging and the importance of identifying ways to slow or reverse aging's effects.

Dr. Stuart Phillips discusses how exercise and nutrition influence skeletal muscle-protein turnover and muscle maintenance throughout the lifespan.

Dr. Matthew Walker discusses the role of sleep in immunity, creativity, and aging.

Rhonda explains NAD+: importance for aging, decline with age, boosters (nicotinamide riboside, nicotinamide mononucleotide), and data in animals and humans.

Broccoli sprouts contain more glucoraphanin, the precursor to sulforaphane, than mature broccoli. Glucoraphanin activates the Nrf2 pathway to protect cells from oxidative stress and damage. In this episode, we describe the basics of sprouting broccoli seeds.

This is a video on how to plausibly increase the sulforaphane created from the glucoraphanin in your broccoli sprouts by up to 3.5-fold.

Dr. Bill Harris discusses the roles that omega-3 fatty acids play in cardiovascular and neurocognitive health.

Dr. Dale Bredesen discusses treatments that may reverse symptoms of mild cognitive decline and Alzheimer’s disease.

Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentia...