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Circadian rhythms are biological timing systems that shape metabolic health, body weight, performance, cognition, and disease susceptibility. Their disruption—through shift work, jet lag, or modern light-and-sleep patterns—is associated with metabolic dysfunction and higher incidence of some…

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Melatonin

Jul 28, 2026

“In a vicious cycle, these disrupted rhythms also contribute to many Alzheimer’s-disease-associated pathways. Supplementing with melatonin may act as a “circadian shield”—a way to maintain normal rhythms in hope of preventing cognitive decline and a way to restore rhythms to slow disease progression.”

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