Search results for metformin

“However, metformin may inhibit exercise-induced health benefits, especially concerning muscle mitochondrial adaptations and hypertrophy. Metformin is safe, even at high doses, and is readily bioavailable in humans.”

“Whether metformin reduces the risk of cancer in healthy people remains to be seen. In this clip, Dr. Rhonda Patrick describes the relationship between metformin and cancer incidence and the relevance for those with type 2 diabetes.”

“However, metformin may inhibit exercise-induced benefits, such as cardiorespiratory fitness and gains in lean body mass. In this clip, Dr. Rhonda Patrick gives her thoughts on whether healthy, active adults should take metformin.”

“Since the long-term consequences of metformin are unknown, a viable approach to depriving cancer cells of glucose, their preferred energy source, might be to limit dietary sugar intake. In this clip, Tim Ferriss and Dr. Rhonda Patrick discuss the anti-cancer properties of the diabetes drug metformin.”

“To circumvent metformin's blunting effect on exercise-derived benefits, some researchers have suggested administering the drug on days when exercise is not performed. However, this may not be a straight forward solution due to the many factors involved.”

“Several randomized controlled trials have suggested that metformin blunts some of the positive effects of aerobic exercise and strength training. Healthy adults taking metformin exhibited 50 percent less improvement in cardiorespiratory fitness following an exercise program.”

“Most of the lifespan-extending benefits have been observed in female mice, with male mice being more sensitive to dosage. In this clip, Dr. Rhonda Patrick reviews the animal research that has been conducted on the potential lifespan-extending effects of metformin.”

“Metformin mimics several pathways associated with caloric restriction and fasting. The body perceives these interventions as stressors and then adapts, ultimately developing metabolic flexibility.”

“In addition, evidence suggests that metformin may prevent cognitive losses, improve mental health status, and reduce the risk of cancer. However, metformin may inhibit exercise-induced health benefits, especially regarding muscle mitochondrial adaptations and muscle hypertrophy.”

“Dr. Rhonda Patrick visits the Kevin Rose Show to discuss metformin, magnesium L-threonate, fish oil and brain health, sulforaphane, goitrogenic activity of isothiocyanates, sauna, and more. Subscribe to the Kevin Rose Show on iTunes. Learn more about Kevin Rose @kevinrose on Twitter. KevinRose.com. The Kevin Rose Show on iTunes. Foundation by True Ventures.”