Search results for epigenetics

“The study found that genes in skeletal muscle have less DNA epigenetic modifications in response to exercise and throughout periods of inactivity (ie. injury). This allows the muscle to grow even bigger following exercise again later.”

“However, the multivitamin did not produce clear effects on three other epigenetic clocks: PCHorvath, PCHannum, or DunedinPACE.”

“Androgens shape more than just male traits—they may also influence the pace of aging. A recent study found that an epigenetic predictor called the androgen clock can precisely track cumulative androgen exposure, offering new insights into how these hormones affect biological aging.”

“This study also confirmed in mice that cold exposure of in male mice results in these metabolic alterations that are transmitted paternally to the offspring via epigenetic changes in sperm cells.”

“A growing body of evidence suggests that sulforaphane's protective effects extend to the brain, where it appears to enhance brain-derived neurotrophic factor (a protein that controls and promotes the growth of new neurons) and inhibits histone deacetylation (an epigenetic modification that influences gene expression).”

“Choline is also one of the major sources of methyl groups that are important in epigenetics. Finally, choline is also a precursor for phosphatidylcholine, the major component of all cell membranes, which affects the structure, permeability and function of cells and is particularly important in neurons since it plays a role in general neurotransmission.”

“The mice also exhibited hypermethylation of specific genes. Hypermethylation is a type of epigenetic modification of DNA that drives gene expression and is associated with increased risk for developing ACF.”

“This systemic inflammation can promote insulin resistance in muscles and fat accumulation in the liver. The downstream effect is accelerated epigenetic aging, a phenomenon that occurs when an individual's epigenetic age exceeds their chronological age.”

“Link to full study. Watch this clip in which telomere expert Dr. Elissa Epel describes how pre-pregnancy health of both parents shapes the health of their offspring through epigenetic mechanisms.”