Search results for dna damage

“DNA damage at telomeres drives senescence in cardiac cells. Removing senescent cardiac muscle cells from the hearts of aged mice, both genetically and using drugs, reduces hypertrophy and fibrosis in aged hearts and restores cardiac health.”

“Fasting also stimulates hormesis, a compensatory defense response following exposure to a mild stressor (short-term food deprivation) that is disproportionate to the magnitude of the stressor. Hormesis triggers a vast array of protective mechanisms that not only repair cell damage but also provide protection from subsequent exposure to more devastating stressors.”

“Telomeres are distinctive structures comprised of short, repetitive sequences of DNA located on the ends of chromosomes. They form a protective “cap” – a sort of disposable buffer that gradually shortens with age.”

“Telomeres get shorter with each year during the aging process but also with increased DNA damage which can be caused by a variety of factors including compounds in air pollution. This was a correlative study so causation can not be established.”

“This compound can damage DNA and proteins within brain cells, leading to cellular dysfunction and cell death. Neuroinflammation: Alcohol also affects the gut-brain axis, which is a direct communication pathway linking your gastrointestinal tract and your brain.”

“Children who do not get adequate sleep have 1.5% shorter telomeres for each hour less that they sleep per night. Telomeres are caps at the end of chromosomes that protect DNA from damage but they get shorter every year and thus are a biomarker for aging.”

“Many of the polyphenols found in coffee have been found to have anti-inflammatory and antioxidant activities. They have also been shown to activate DNA repair and autophagy, the clearing away of damaged components inside of cells.”

“From the article: > "Stem cells use ascorbate to regulate the abundance of certain chemical modifications on DNA, which are part of the epigenome," said Dr. Michalis Agathocleous, lead author of the study. [...]”

“Early findings illuminated the role of calorie restriction in modulating adaptive cytoprotective mechanisms that enhance metabolic response and reduce oxidative damage and inflammation – factors related to increased longevity and decreased risk of age-related disease.”

“Telomeres and how they relate to aging. How antioxidants prevent damage to DNA, lipid membranes, and proteins in the body. Supplemental vitamin E and the interaction between alpha and gamma tocopherols.”