Search results for lactate

“Since the long-term consequences of metformin are unknown, a viable approach to depriving cancer cells of glucose, their preferred energy source, might be to limit dietary sugar intake. In this clip, Tim Ferriss and Dr. Rhonda Patrick discuss the anti-cancer properties of the diabetes drug metformin.”

“In animal models, mice fed a medium-chain triglyceride supplemented ketogenic diet ran farther and faster on a treadmill than animals fed standard chow. In humans, the data supporting the benefit of ketones on performance are less clear.”

“The body has elegant mechanisms that allow it to utilize non-carbohydrate substrates to generate glucose. Gluconeogenesis is a metabolic pathway in which the liver produces glucose from non-carbohydrate substrates including glucogenic amino acids (from protein) and glycerol (from lipids).”

“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”

“However, dietary strategies, pharmaceuticals, and some supplements may reduce ApoB levels. In this Aliquot – a follow-up to Aliquot #81 – Dr. Peter Attia and I talk about some of the nutritional, pharmaceutical, and supplemental approaches to reduce ApoB.”

“In more than 25,000 adults who reported no leisure-time exercise, a median of three one- or two-minute bouts per day was associated with 38 to 40 percent lower all-cause and cancer mortality and 48 to 49 percent lower cardiovascular mortality compared with no VILPA.”

“In 25,241 adults who reported no structured exercise, a median of three one- or two-minute vigorous lifestyle bouts per day was associated with 38% to 40% lower all-cause and cancer mortality and 48% to 49% lower cardiovascular mortality.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“01:36:35 - How increased muscle mass helps achieve lower blood sugar levels – reducing overall mortality – and the potential for suboptimal glycemic control long before doctors identify it. 01:52:28 - Peter's 80% zone 2 / 20% VO2 max training protocol.”

“Mitochondrial biogenesis, the formation of new mitochondria within cells, is boosted by exercise to meet heightened energy needs. While all forms of exercise can promote this process, high-intensity interval training (HIIT) might accelerate the surge in mitochondrial content more swiftly than continuous exercise.”