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“The importance of time of day for this type of intermittent fasting is still an interesting open question, especially since there’s a lot of advocacy for late eating among 16:8 advocates, however, insulin sensitivity usually declines later in the day (and is exacerbated by the production of melatonin, which has an effect of shutting off insulin secretion).”

“A new study has found that a tiny region in the brain called the locus coeruleus may provide the link between openness and better cognitive health. People with greater locus coeruleus integrity demonstrated more openness and – interestingly – had higher intelligence.”

Dr. Ruth Patterson discusses the role of fasting in the prevention and survivorship of breast cancer.

“Here’s an interesting report that didn't make it into this issue of the Digest. Robust research highlights magnesium's crucial role in managing stress responses, revealing that stress can promote magnesium loss.”

“The same research group previously found that tea consumption was linked to a 50% reduction in cognitive decline. Since this was not a randomized controlled trial it is difficult to establish causation but the results are interesting and worth sharing!”

“Insulin in the brain improved the functional connectivity between the hippocampus which suppressed the feeling of hunger and improved insulin sensitivity in the body. This very interesting study shows that insulin in the brain may have an important role for satiety and insulin sensitivity in the body.”

“Short bursts of high-intensity exercise do not use mitochondria which means glucose is the only energy source for anaerobic exercise. This is an interesting study but still, a pilot trial and more data are needed before conclusions can be made.”

“Here’s an interesting report that didn't make it into this issue of the Digest. Physical inactivity is a principal driver of Alzheimer's disease. However, resistance exercise elicits structural changes in brain regions affected by Alzheimer's, including those involved in communication, coordination, and memory, such as the cingulate white matter tracts and the hippocampus.”

“We know that circadian rhythm regulates metabolism, hormone production, neurotransmitter production and more. This article covers another area that circadian rhythm also regulates: drug metabolism. Interesting read!”

“Here are some interesting reports that didn't make it into this issue of the Digest. Taste receptors are specialized chemosensory cells found in the gut, airways, and testes that mediate a wide range of protective responses.”