Search results for gut

“Cruciferous vegetables such as broccoli contain a compound called indole glucosinolate that is converted into indolocarbazole. The indolocarbazole compound binds to a receptor in the intestinal lining which then helps maintain a healthy balance in the gut microbiome, immune surveillance, and enhances host barrier function.”

“This study was able to pinpoint the 10% increase in body mass to altered gut bacteria by transplanting the gut microbiome from mice given the risperidone drug to the control mice and the same effect occurred. Risperidone is a common drug that is used to treat autism, bipolar disorder, and schizophrenia in adults and children and its prescribing rate has increased 8-fold in the last 2 decades.”

“Overnutrition often leads to obesity and inflammation, with the gut being a powerful driver of the inflammatory process. Studies of centenarians suggest that lower levels of inflammation are associated with longevity.”

“More research needs to be done to investigate how much of a role high sodium intake plays in the relative loss of Lactobacillus strains from gut microbiomes and development of hypertension and autoimmunity.”

“Researchers exposed 38 strains of human gut bacteria to a range of PFAS, testing concentrations from nanomolar to 500 micromolar. Then, they assessed how the bacteria took up the chemicals and how those chemicals affected bacterial function.”

“The microbiome is the entire population of microorganisms that live on or in the body. There is some evidence that certain signatures of gut population levels can have a strong correlative and even causative relationship with health status.”

“Evidence suggests that toxic exposures increase kidney disease risk. A recent study found that higher exposure to PFAS—so-called "forever chemicals"—was linked with decreased kidney function in young adults, potentially mediated by gut bacteria and metabolite changes.”

“Experiments in mouse models have suggested that intermittent fasting produces changes in circadian biology and remodeling of the gut microbiota, but further research in humans is needed. The investigators recruited two cohorts of participants.”

“The inclusion of active myrosinase is critical in clinical trials because although myrosinase-producing gut bacteria can convert unhydrolyzed glucosinolates to their cognate isothiocyanates, the conversion rate is highly variable and subject to interindividual differences in gut bacteria populations.”

“Myelin is essential for normal brain function and is altered in multiple sclerosis), and altered brain structure. This was partly reversed by introducing the gut bacteria.”