Search results for fat

“For people who smoke, cessation is the priority; risk declines after quitting even when exposure has already occurred. Excess body fat can affect insulin, sex hormones, and inflammatory signaling, so body composition and movement belong in the same risk-reduction framework.”

“Cold exposure, which induces hypothermia, causes white fat to convert to beige fat, a process known as "browning" (or "beiging"). Conversely, findings from a recent study suggest that heat exposure, which induces hyperthermia, also promotes browning of white fat.”

“Instead, pairing NR with interventions that actively mobilize fat and then testing whether it adds benefits is a logical next step. Mechanistically, however, he ties lipid mobilization to NAD/NADPH being "under attack" in metabolic diseases.”

“Studies in animals and humans suggest that brown fat can improve glucose and insulin sensitivity, increase fat oxidation, and protect against diet-induced obesity. Cold exposure increases brown fat volume and metabolism and drives glucose uptake.”

“Insulin resistance impairs this process, resulting in higher blood sugar and increased fat release into the bloodstream. Controls showed lower de novo lipogenesis (the liver's production of new fat from non-fat sources) at night, while MASLD participants kept this pathway elevated.”

“Greater visceral abdominal fat was independently associated with increased markers of cerebral small vessel disease in participants without a history of symptomatic cerebrovascular disease.”

“Consequently, the latter of these formulations must be taken with a high-fat meal to stimulate the activity of these enzymes. In contrast, free fatty acid formulations do not require enzymatic digestion and can be taken without regard to food intake.”

“It included 4,984 men aged 20 to 59, each with a single blood measurement of total testosterone. Researchers compared statistical models relating testosterone to age alone with models that also included body fat or waist circumference.”

“However, some donors' cells elicited responses to protein (9%) and fat (8%) greater than their response to carbohydrates. Cells from donors with type 2 diabetes exhibited diminished responses to carbohydrates and fats, but their protein response was preserved.”

“The authors of the study posited that failure to publish negative or inconclusive results can contribute to skewed research priorities and public health interventions. Link to full study. Listen to this podcast in which Dr. Rhonda Patrick discusses the controversy surrounding saturated fat intake and cardiovascular disease risk.”