What FoundMyFitness Has Covered
PremiumEstrogen is presented as a context-dependent hormone whose effects vary with metabolic state, reproductive stage, and exposure. In obesity and diabetes, elevated estrogen alongside insulin and inflammation may increase breast-cancer risk by promoting tumor-cell growth and…
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Based on available source text from 8 of the first 10 results.
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High estrogen and insulin associated with breast cancer growth in diabetes & obesity | Ruth Patterson
“Obesity promotes inflammation and elevated levels of the hormones estrogen and insulin, which may lead to an increased risk of breast cancer. Acting as growth factors, both estrogen and insulin can promote tumor cell growth, as well as undermine the innate defense system that removes damaged cells from the body.”
Alcohol
“Regarding testosterone, low to moderate intake may elevate testosterone levels while heavier consumption decreases it in men. Chronically, alcohol consumption reduces GnRH, LH, testosterone, and progesterone and increases estrogen/estradiol and FSH.”
Choline
“While rare, choline deficiency can occur, particularly in pregnant and lactating women, postmenopausal women with lower estrogen levels, and individuals with genetic variants affecting choline metabolism.”
Breast milk and breastfeeding
“During pregnancy, little milk secretion occurs due to the high progesterone to estrogen ratio, which favors breast growth. By late pregnancy, however, some women can express colostrum (see below). Stage II lactogenesis occurs in the first four days postpartum.”
Depression
“These phenotypic traits were associated with lower serotonin receptor levels and lower hippocampal volume, the latter of which was more extensive in postmenopausal monkeys, suggesting that ovarian hormones, including estrogen, may lessen depression risk.”
Sauna
“BPA is an endocrine disruptor that can mimic naturally occurring hormones in the body like estrogens, androgens, and thyroid hormones, potentially altering normal hormonal signals. High levels of urinary BPA are associated with increased risk for cardiovascular disease and diabetes.”
Omega-3 fatty acids
“Influence insulin sensitivity. Alter estrogen synthesis. Interestingly, the Selenium and Vitamin E Cancer Prevention Trial (SELECT) reported that higher plasma omega-3 fatty concentrations were associated with an increased risk of developing prostate cancer.”
Estrogen-mimicking compound GLP-1-estrogen found to inhibit binge eating behavior in mice by carrying estrogen into serotonin region of the brain.
“"We can speculate that in women who develop binge eating who also happen to have irregular menstrual cycles, it is probably because their estrogen function is somehow damaged, which is what leads to the development of binge eating," said the study's lead author.”
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