Search results for genetics

“The aggregate of these exposures is referred to as the "exposome" – the totality of non-genetic exposures that a person experiences during a lifetime – and includes nutritional, environmental, microbial, financial, and emotional factors.”

“These findings provide a better understanding of the genetics underlying omega-3 fatty acid metabolism in diverse genetic groups and underscore the importance of considering ancestry in genetic studies.”

“These genetic differences may also drive alcohol consumption and tobacco use, the research showed. Researchers analyzed the genetic makeup of more than 6,500 people to determine if they carried a particular gene variant of FGF21 – a hormone produced in the liver – called rs838133.”

“The researchers applied a method called Mendelian randomization, which uses naturally occurring genetic differences to explore cause-and-effect relationships. Because inherited genetic variants are fixed at conception, they create natural groups that are largely not shaped by later habits or environmental factors.”

“The authors collected genetic data, clinical data measuring intraocular eye pressure, and self-reported dietary data regarding coffee and tea consumption from more than 100,000 participants enrolled in the United Kingdom Biobank study. Next, the authors calculated each participant's polygenic risk score, which estimates an individual’s genetic susceptibility to a specific disease.”

“The patients provided blood samples for genetic analysis and completed self-assessment questionnaires about depression, hopelessness, impulsivity, and the severity of their alcohol use. The authors followed up with participants for approximately one year to assess whether they had relapsed.”

“A recent study found that lifestyle interventions reduce the risk of developing diabetes, especially among those at high genetic risk. The study involved nearly 1,000 middle-aged men with metabolic syndrome—a constellation of health conditions that increases the for diabetes.”

“A recent study found that the exposome contributes far more to premature death and age-related diseases than genetic risk alone. Researchers analyzed data from nearly 500,000 people enrolled in the UK Biobank to measure the exposome's role in aging.”

“A higher genetic score for longevity was linked to a 15% lower risk of death, yet the protective associations of a healthy diet were largely similar across genetic risk groups. The DRRD appeared especially beneficial among people with a lower genetic predisposition to long life.”

“A healthy lifestyle was classified as regular physical activity, a healthy diet, not currently smoking, and moderate alcohol consumption. This is more evidence that lifestyle plays a very important role in disease risk even in people with a high genetic risk for certain diseases like Alzheimer's disease.”