Search results for ketogenic diet

“Learn more about the health effects of beta-hydroxybutyrate in our overview article. Link to full publication. Ketogenic diet and beta-hydroxybutyrate improve gene transcription and reduce intellectual disability in inherited epigenetic machinery disorder.”

“00:22:54 - How to start a ketogenic diet, which biomarkers to measure to assess suitability, and ideas on how to adjust the diet for APOE4 genotype. 00:43:24 - Why glucose can drop into hypoglycemic ranges with high-dose ketones.”

“Ketones increase in concentration in the brain, liver, heart, muscle, and other tissues during exercise, fasting, and carbohydrate restriction on a ketogenic diet. Research demonstrating strategies to increase butyrate and BHB includes: Omega-3 fatty acid consumption increased the concentration of butyrate-producing bacteria in the gut.”

“The ease of implementing and following a ketogenic diet varies from person to person, depending on several factors, including fitness level, disease state, and lifestyle. The gold standard to determine whether someone has achieved a state of nutritional ketosis is to measure blood ketone levels.”

“Surprisingly, no evidence suggests higher levels of LPS leak into circulation during a ketogenic diet, likely due to the profound metabolic changes induced during ketosis. In addition, beta-hydroxybutyrate, a ketone produced during a ketogenic diet, may travel to the colon and nourish the colonocytes.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Fasting or beta-hydroxybutyrate administration reduces the production of senescent cells. Ketogenic diets, fasting, and exercise have all demonstrated the ability to extend healthspan and lifespan, possibly through mechanisms mediated by beta-hydroxybutyrate (BHB).”

“Dr. D'Agostino further describes studies in his laboratory that combined a ketogenic diet with mild caloric restriction. Animals fed in this manner had enhanced cognition. Whether these effects will translate to humans remains to be seen.”

“However, Dr. D'Agostino clarifies that it might not be optimal to ingest ketone supplements daily, and he describes his experience with elevated liver enzymes following high dose supplementation. In this clip, Dr. Dominic D'Agostino discusses the supplements he thinks pair well with a ketogenic diet.”

“The impact of the ketogenic diet on gut bacteria has not been actively studied. In animal models high-fat diets are thought to provoke the release of endotoxin from bacterial cell membranes resulting in negative health consequences. In this clip, Dr. Dominic D'Agostino and Dr. Rhonda Patrick discuss the ketogenic diet and its implications for gut health.”