Supplementation with 400 IU of vitamin D during the first year of life led to more muscle mass & less body fat as toddlers.
“The main source of vitamin D for infants in the first year of life is breast milk. However, if a mother has inadequate levels of vitamin D herself then the infant will not get a sufficient amount of vitamin D from the milk.”
NAD+
“When oral tryptophan was the source, the liver produced NAD+ for local use and broke down into nicotinamide, as described above. Nicotinamide traveled to other tissues, such as the muscles, brain, and gut, which used salvage pathways to convert it back to NAD+.”
New 20-page report on cryotherapy just released! Cold shock boosts norepinephrine up to 5-fold & increase type of immune cell that kills tumor cells.
“Rhonda discusses how cold exposure increases norepinephrine up to 5-fold in the brain and what the temperature and duration needed to do this are, how norepinephrine has an effect on mood, vigilance, focus, and attention, how cold exposure increases cold shock proteins including one in the brain that repairs damaged synapses and in muscle prevents atrophy…”
Aerobic exercise (wheel running) prevents cancer tumor formation, growth, and cachexia (cancer weight loss) in mice
“These NK cells are recruited to the site of the tumor by the protein IL-6, secreted by active muscles. The NK cells can then infiltrate the tumor, slowing or completely preventing its growth.”
Using sauna 4-7x per week lowered dementia risk by 66% & Alzheimer's risk by 65% after adjusting for diet/lifestyle.
“Anyone that follows me knows that I talk about saunas ALOT. I have a couple of videos where I discuss the effects of the sauna on longevity and in muscle mass and endurance. I discuss the role of heat shock proteins in both videos.”
Resistance training notably improves sleep quality in older adults, outperforming both aerobic and combined exercises.
“These findings suggest that resistance training does more than build muscle—it also improves sleep. Resistance training builds bone, too, a critical component of aging well. Learn more in this clip featuring Dr. Brad Schoenfeld.”
New insights on how some individuals with obesity can lose weight
“Both groups participated in a supervised, six-week exercise program that included both aerobic and resistance exercises, performed three times per week. The investigators assessed the women's body composition and metabolic markers and collected muscle tissue samples for biopsy.”
Episode
Joe Rogan Experience #901 - Dr. Rhonda Patrick
“02:46:00 - Statins can cause muscle atrophy. Study. 02:47:00 - How sugar companies paid researchers for decades to falsify research about saturated fats in order to promote sugar consumption.”
Toll-like receptors
“Loss of insulin sensitivity in muscle increases blood sugar levels, contributing to type 2 diabetes and cardiovascular disease development. The endothelial cells that line blood vessels are also sensitive to the ROS produced by excessive TLR4 activation.”
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