Search results for aging

“Sodium keeps our hearts beating, our muscles moving, and our nerves firing—but it's also one of the most debated nutrients in health. While sodium is essential for survival, too much or too little can tip the scales toward problems like high blood pressure or fatigue.”

“The heart becomes smaller and less compliant with sedentary aging, which can limit how effectively it fills during exercise. In this clip from Dr. Rhonda Patrick's appearance on PBD Podcast, she describes a two-year randomized trial in healthy but sedentary adults ages 45 to 64.”

“The progressive program built toward four to five aerobic sessions per week, including a weekly Norwegian 4x4 interval workout, rather than asking participants to begin with the final volume. The randomized trial increased VO2 max by 18% and improved left-ventricular compliance, reversing measured cardiac stiffness associated with sedentary aging.”

“In Part I of this three-part Aliquot series, creatine expert Dr. Darren Candow and I examine creatine through the lens of two critical systems—muscle and bone—and unpack how creatine supplementation affects muscle quality, physical function, and even skeletal health, particularly in older adults.”

“When these bacteria digest fiber, they produce short-chain-fatty-acids (SCFAs), including butyrate, as byproducts. > "Butyrate is of interest because it has been shown to have anti-inflammatory properties on microglia and improve memory in mice when administered pharmacologically," [...]”

“This 2018 review presents a review of the evidence demonstrating osteocalcin's roles in the brain.”

“This 2023 study found that exercise dampened inflammatory pathways and restored immune function in old animals.”

“Mitochondria are best known for their energy-producing roles, but they also help regulate cellular metabolism, signaling, and apoptosis (programmed cell death). As a result, mitochondrial health is intrinsically linked to overall health.”

“Dr. Unutmaz frames these converging advances as a reason to protect health now, so that people are better positioned to benefit from future progress in cancer treatment, regenerative medicine, and healthy aging.”

“The vascular evidence is primarily mechanistic or animal evidence. Blood-brain-barrier breakdown is associated with brain aging, neuroinflammation, and early dementia markers, but that association does not prove that exercise-derived lactate prevents dementia.”