Search results for dairy

“Histone deacetylase (HDAC) inhibitors, such as the ketone beta-hydroxybutyrate (BHB), are compounds that help release histones, open chromatin, prevent loss of gene expression with aging, and may even lengthen lifespan.”

“Multiple age-related inputs can keep innate immune pathways active, including the senescence-associated secretory phenotype, mitochondrial damage and oxidative stress, debris released by injured cells, visceral adipose tissue inflammation, chronic infections, increased intestinal permeability, and dysbiosis.”

“Parkinson's disease is a progressive neurodegenerative disorder characterized by loss of dopamine-producing neurons, motor impairments, and the accumulation of alpha-synuclein, a neuronal protein that regulates synaptic vesicle movements and neurotransmitter release.”

“Cold exposure offers surprising health benefits, and emerging evidence suggests that whole-body cryotherapy enhances wellness and even improves sleep. A recent study found that five days of daily cryotherapy improved mood, reduced anxiety, and enhanced sleep quality in healthy young adults.”

“Glyphosate-exposed Alzheimer's-prone mice had lower survival rates, more difficulty in spatial memory tasks, and increased markers of Alzheimer's pathology, including larger and more numerous amyloid-beta plaques and higher levels of phosphorylated tau protein.”

“However, a recent study has uncovered a more alarming issue: Microplastic contamination is pervasive in these popular beverages. Researchers analyzed the microplastic content in a popular soda brand purchased in various US locations: Atlanta, Los Angeles, Chicago, and Washington, DC.”

“However, two small, randomized, double-blind, placebo-controlled experiments in which participants received BHB supplements (as ketone salt or ketone monoester) found that various markers of NLRP3 inflammasome activation, including caspase-1 and interleukin 1-beta, increased, suggesting that the ketones may have unintended proinflammatory effects.”

“In addition, a randomized, placebo-controlled, double-blind trial involving people diagnosed with mild-to-moderate dementia due to Alzheimer's disease found that participants who took a resveratrol supplement twice a day (up to 1 gram) for one year exhibited reduced levels of MMP9, a neurological inflammatory marker associated with increased neurodegeneration and inflammation.”

“Children with overweight or obesity can develop nonalcoholic steatohepatitis (NASH) – an inflammatory condition in which fat builds up in the liver, replacing healthy tissue. Without intervention, NASH can progress to more advanced forms of liver disease, including cirrhosis and cancer.”

“Using isotope tracers that allowed them to distinguish NAD+ made directly from NR or NMN versus NAD made from nicotinamide, NR, or NMN, they found that a low oral dose of the precursors (50 milligrams per kilogram body weight, mg/kg/bw) produced very low levels of NAD+ made directly from NR and NMN in the liver but not in other tissues.”