Search results for glucoraphanin

“Of those with poorly regulated disease, 17 had obesity. Nearly all of the participants took metformin, a common blood glucose-lowering drug. Participants received either an oral placebo or glucoraphanin-rich broccoli sprout extract every day for 12 weeks.”

“The double-blind study randomly assigned 41 men with prostate cancer awaiting surgery to remove the prostate to receive either a daily placebo or a broccoli-derived supplement containing 240 mg of glucoraphanin plus myrosinase for four weeks.”

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”

“Sulforaphane switches on mechanisms that protect against cancer and other environmental insults. Sulforaphane is produced when the plants' cells are damaged by chewin or chopping and some culinary "hacks" favor its production.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Although many supplement manufacturers do not take steps to preserve the integrity of their products and some have made misleading claims about their products' efficacy, a few reputable manufacturers produce quality supplements that have been used in clinical trials.”

“The seeds of cruciferous vegetables are particularly good sources of isothiocyanates, but care must be taken to preserve the myrosinase, which is heat sensitive. In this clip, Dr. Jed Fahey describes the chemical reaction that produces isothiocyanates and cautions against preparation techniques that might inhibit their production.”

“While sulforaphane is available in supplement form, it is derived naturally from a variety of cruciferous vegetables such as Brussels sprouts, kale, and mustard greens, with the highest quantities available from broccoli sprouts.”

“Robust clinical evidence has demonstrated that sulforaphane increases the production of mercapturic acid metabolites of benzene and acrolein, known carcinogens present in air pollution and smoke from fires.”

“The conversion of glucosinolates to their cognate isothiocyanates via myrosinase-driven hydrolysis is not a direct path; rather, it occurs in a stepwise fashion, yielding a variety of intermediate bioactive compounds that can rearrange to form the final product.”