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Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Inflammation is a critical element of the body’s immune response. Chronic inflammation, which occurs on the cellular level in response to toxins or other stressors, plays a key role in the development of many diseases, including depression.”

“In a randomized trial of 57 children with autism spectrum disorder, a caregiver-rated secondary behavior scale improved and biomarker changes involved glutathione, mitochondrial, inflammatory, and heat-shock pathways, while the primary clinical outcome was similar between groups.”

“Parents and care providers of children and adults with autism often report that fever temporarily ameliorates the altered behavioral patterns of their charges. Emerging scientific data corroborates these reports, suggesting that triggering the body's fever response might offer promise as a therapeutic strategy for people with autism.”

“Parents and care providers of children and adults with autism often report that fever temporarily ameliorates the altered behavioral patterns of their charges. Emerging scientific data corroborates these reports, suggesting that triggering the body's fever response might offer promise as a therapeutic strategy for people with autism.”

“Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in humans. Some of these effects are mediated by increased glutathione, one of the body's most potent antioxidants, to promote brain health.”

“Inflammatory markers, such as cytokines, are elevated in people with depression. Investigators observed that a subset of patients treated for hepatitis C using repeated doses of interferon-alpha, which stimulates inflammation, developed depression.”

“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”

“Choosing a supplement that contains both glucoraphanin (the precursor to sulforaphane), as well as myrosinase (the enzyme that converts glucoraphanin to sulforaphane), is crucial to ensuring optimal sulforaphane delivery.”

“Acute activation of the immune system (from exercise or sauna use for example) can temporarily reduce inflammation and the depression that can come with it. The segments brought to you by this episode of The Aliquot feature professor of psychiatry Dr. Charles Raison.”