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Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“00:15:42 - How periodic prolonged fasting or the fasting-mimicking diet may be able to render cancer cells more vulnerable while conferring stress resistance to healthy cells, a quality known as differential stress resistance.”

“Extensive research shows a clear distinction between filtered and unfiltered coffee methods, especially concerning cancer and cardiovascular health. Filtered vs. unfiltered coffee Filtered coffee is strongly associated with protective effects against cancer.”

“When this barrier breaks down, as in, intestinal permeability, also known as "leaky gut," microbes and their metabolites translocate out of the intestinal lumen and influence the health and function of distant tissues, such as the brain, connective tissues, sometimes promoting a state known as "metabolic endotoxemia."”

“IGF-1 participates in a complex pathway known as the growth hormone/IGF-1 axis, where it exerts its role to accelerate aging. In this clip, Dr. Valter Longo explains how certain macronutrients influence the insulin/IGF-1/growth hormone axis to modulate aging in many cell types.”

“Emerging evidence suggests that IGF-1 also regulates the aging process via its influence on growth hormone. In this clip, Dr. Valter Longo describes the IGF-1 pathway and explains how defects in the pathway influence disease risk.”

“These experiments do not show that every hallmark of aging can be reversed or that whole-body rejuvenation is currently achievable. Delivery, cancer risk, tissue specificity, durability, and the influence of the aged tissue environment remain major challenges.”

“Dr. Patrick explains some of the early evidence that suggests the value prolonged fasting (48+ hours) may have from the standpoint of tissue rejuvenation and healthspan maintenance, as well as relevance for other more specific conditions.”