Related Episodes for Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”

“Inflammation is a critical element of the body’s immune response. Chronic inflammation, which occurs on the cellular level in response to toxins or other stressors, plays a key role in the development of many diseases, including depression.”

“Researchers treated patients with major depressive disorder with heat so that their core body temperature reached temperatures equivalent to those experienced with sauna use. Following just one treatment session, subjects experienced elevations in mood that lasted for several weeks.”

“Five grams of creatine per day increased total sleep duration on resistance-training days compared with placebo, while the groups did not differ in overall sleep quality. The result introduces sleep as a promising new area of creatine research.”

“Since then, countless studies have tested Pauling's theories about vitamin C, colds, and cancer (and many others), and a substantial body of evidence has emerged, identifying critical roles for vitamin C in immune function, cardiovascular and respiratory health, cognitive development and preservation, and many other aspects of human health.”

“In this clip from Q&A #70, Dr. Rhonda Patrick organizes cancer prevention around the largest modifiable foundations: avoid tobacco, maintain a healthy body composition, and stay physically active.”

“In a small crossover trial involving people with insulin resistance, six one-minute intense intervals performed before the three main meals improved daily glucose control compared with one continuous 30-minute session.”

“In more than 2,000 adults ages 51 to 80, higher Sitting-Rising Test scores were associated with longer survival, making floor-transfer ability a useful marker of functional capacity. Floor time can include cross-legged sitting, kneeling, side-sitting, or sitting with the legs extended.”

“Dr. Schoenfeld says the situation is likely more complex and nuanced. For example, a marathon runner will have difficulty with hypertrophy, probably due to overtraining rather than intracellular signaling negatively affecting muscle development.”

“A growing body of scientific evidence suggests that there's a correlation between nutrition, exercise, sleep, and stress management and having longer telomeres. Identifying the mechanisms that drive these correlations has proven challenging, but a few candidates stand out, including improvements in immune function and metabolic health.”