Related Episodes for Does drinking coffee break your fast? | Satchin Panda

“In a double-blind randomized trial of 191 adults with borderline-high cholesterol, 3 grams per day of high-molecular-weight oat beta-glucan—taken as 1 gram three times daily for four weeks—reduced LDL cholesterol by about 6% and estimated 10-year Framingham cardiovascular disease risk by about 8% compared with a rice-powder control.”

Dr. Rhonda Patrick discusses organic produce, fasting-mimicking diets, sleep, sauna, sunscreens, red light therapy, reverse osmosis water, and fiber.

“In a small trial involving adults with obesity, a ketone monoester improved one processing-speed task and selected brain blood-flow measures, providing an early signal for further research. Temperature can also shape alertness and sleep preparation.”

“When most people think about certain lifestyle factors that affect insulin sensitivity and blood glucose levels, they think about macronutrient composition, or calories, or fasting, or exercise (and lack of), but they don’t often think about sleep.”

“The hydrolytic conversion of glucoraphanin to sulforaphane requires myrosinase, an enzyme co-located within the leaves, stems, and other components of the plants in which it is found. In humans, myrosinase-producing gut bacteria can convert unhydrolyzed glucosinolates to their cognate isothiocyanates, as well.”

“Based on findings from more recent studies using stable isotopes, which more accurately assess muscle protein anabolism and catabolism, Dr. Phillips believes that eating 1.2 to 1.6 grams of protein per kilogram of bodyweight (about 0.5 to 0.7 grams per pound) is likely optimal for muscle protein synthesis, especially as one ages.”

“Human trials suggest that alpha-lipoic acid can modestly improve selected lipid measures. A dose-response meta-analysis of 12 studies found reductions in total cholesterol, LDL cholesterol, and triglycerides across doses from 300 to 1,200 milligrams per day.”

“In contrast, a five-week trial in 181 people with diabetic polyneuropathy found that oral alpha-lipoic acid improved symptom scores, with more nausea, vomiting, and vertigo at higher doses. PQQ has a much smaller human evidence base.”