Related Episodes for Do healthy people benefit from intermittent fasting? | Dr. Mark Mattson

“In this Knowledge Project excerpt, Dr. Rhonda Patrick distinguishes Finnish sauna protocols near 174–175°F from lower-temperature infrared sauna, which may require longer exposure. Dose depends on temperature, humidity, duration, acclimation, hydration, and health.”

“Although whole-body hyperthermia and sauna use share some similarities, whole-body hyperthermia sessions are typically longer (an hour or more) and the participant's head is spared (often kept cool with ice or cool cloths), prolonging the participant's tolerance to the intense heat.”

“A staggering 60% of all calories Americans consume come from ultra-processed foods that fail to induce proper satiety, remain cheaper than whole foods, and hijack our dopamine reward pathways, pushing us to overeat, incentivizing unhealthy food choices, and reinforcing addictive eating behaviors.”

“Exercise promotes the release of insulin-like growth factor-1 and its downstream targets, growth hormone and brain-derived neurotrophic factor, to drive muscle and neuron growth. Sauna use increases these factors, too, and when used post-exercise, may have a synergistic effect to improve cardiovascular, musculoskeletal, and neurological health.”

“When most people think about certain lifestyle factors that affect insulin sensitivity and blood glucose levels, they think about macronutrient composition, or calories, or fasting, or exercise (and lack of), but they don’t often think about sleep.”

“In a placebo-controlled study of eight healthy adults, adrenaline infusion lowered plasma magnesium, and levels had not recovered one hour later. Investigators proposed a shift into cells after beta-adrenergic stimulation; the study did not measure cortisol, urinary loss, total-body depletion, or clinical deficiency.”

“Diet plays a key role in the prevention of Alzheimer's disease. The Ketoflex 12/3 diet, a form of time-restrictive eating that limits the period during which a person eats to a 12-hour window at least three hours before bedtime, promotes the production of ketones.”

“The menus were matched for presented calories, energy density, total sugar, sodium, and fiber, but not added sugar: much more of the ultra-processed diet's sugar was added rather than contained in fruit. Protein was also only approximately matched, at about 14% versus 15.6% of calories.”

“In a short intervention in 29 healthy young men, a daily sugar-sweetened beverage increased fasting glucose, C-reactive protein, and atherogenic LDL features within three weeks; this was a biomarker study, not a cancer trial.”

“Since then, countless studies have tested Pauling's theories about vitamin C, colds, and cancer (and many others), and a substantial body of evidence has emerged, identifying critical roles for vitamin C in immune function, cardiovascular and respiratory health, cognitive development and preservation, and many other aspects of human health.”