Related Episodes for HIIT – contraindications and considerations for older adults | Dr. Martin Gibala

Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...

“A four-week pilot study in people with type 2 diabetes reported improved insulin-stimulated glucose disposal after oral alpha-lipoic acid, while a three-week randomized trial found that intravenous 600 milligrams per day reduced diabetic neuropathy symptoms.”

“However, the ability to translate data from non-human animals to humans can be limited and the use of laboratory animals can raise ethical concerns. In this clip, Dr. George Church describes the pros and cons of animal research and how we could move beyond its use with advanced technologies.”

“Approximately 25 percent of people living in the United States carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

“Dr. Krauss explains how some people might be inappropriately prescribed statins while other people should be taking statins. In addition, his current research is investigating whether statins can increase the risk of diabetes, especially for women.”

“Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS Research Foundation which aims to find technologies that can repair the various types of damage that occur during the aging process. Learn more about Dr. Aubrey De Grey SENS Research Foundation.”

“For instance, while the U.S. has high obesity rates, its rates of type 2 diabetes remain modest compared to countries like Singapore, India, and many Middle Eastern nations—populations that, on average, tend to have "fatter fat cells" and therefore develop metabolic complications at lower body mass indices (BMIs).”

“A common feature of heart disease is arrhythmia, an irregular heartbeat. Interestingly, research in fruit flies has shown that unhealthy lifestyle behaviors, such as poor sleep and diet, increase the risk of developing arrhythmias.”

“Unique qualities of the marine omega-3 fatty acids EPA and DHA There are several omega-3 fatty acids, but the ones that have the greatest relevance for human health are the two identified in the Inuit's blood – EPA and DHA – as well as alpha-linolenic acid (ALA), which is found in a wide variety of seeds, nuts, and their oils.”

“In a separate analysis of seven intervention trials involving people with type 2 diabetes, HbA1c fell by about 0.71 percentage points, total cholesterol by 23 mg/dL, and LDL cholesterol by 22 mg/dL.”