Related Episodes for Nutrigenomics, Epigenetics, and Stress Tolerance (IHMC Talk #1)

“In this clip, Drs. Levine and Patrick discuss definitions of aging used in science and why biological aging matters to scientists. Dr. Levine shares the hallmarks of aging that help researchers determine someone's biological age, what drives accelerated aging, and what epigenetic modifications such as CpG methylation say about the aging process.”

“The stability of DNA methylation patterns - in terms of sample reliability - makes the use of epigenetic clock data an attractive tool in the hands of researchers investigating aging around the world.”

“Sure, those dates on the calendar pass at the same rate for everybody, but some people appear to age slower (or faster) than others – with vastly different age-related physical changes and disease risks.”

“However, a growing body of evidence suggests that pre-pregnancy health of both parents shapes the health of their offspring through epigenetic mechanisms, which are influenced by nutrition, stress, and other environmental factors.”

“Rhonda and Steve discuss calorie restriction, GLP-1 therapy, multivitamins, omega-3s, vitamin D, vegetables, red meat, exercise, heat exposure, sleep, social connection, consumer testing, AI-built clocks, partial reprogramming, and why no single intervention is likely to stop aging on its own.”

“Scientists are exploring a wide range of cutting-edge therapies aimed at understanding and manipulating the complex processes underlying these hallmarks, including epigenetic aging clocks and pluripotent stem cells.”

“In part I of this two-part series on the future of aging research, we discussed the hallmarks of aging and the cutting-edge therapies aimed at understanding and manipulating the complex processes underlying these hallmarks, including epigenetic aging clocks and pluripotent stem cells.”

“Recent discoveries in the field of epigenetics suggest we might be able to slow aging, based on the realization that not everyone ages at the same rate. Evidence suggests that drugs or other medical procedures can slow epigenetic aging, but other factors, such as diet and disease states influence it too.”

“But could aging become reversible in the future? Technologies like interrupted cellular reprogramming, in combination with future advances in the field of epigenetics, offer the promise that scientists may eventually be able to develop the means to reverse aging.”

“Scientists are using artificial intelligence to analyze databases of facial images from people of different ages matched with metabolites in order to develop biomarkers. Other researchers are studying blood markers from people of different ages to create an aging curve.”