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Related Episodes for Will intermittent fasting affect human lifespan? | Dr. Mark Mattson

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How Daily Habits and Nutrients Can Reduce Migraine Frequency

Dec 3, 2025

“In another randomized trial, advice to drink an additional 1.5 liters of water daily improved migraine-specific quality of life, even though headache-day counts did not clearly change. Selected nutrients may help some people as part of a broader prevention plan.”

nutrition exercise sleep omega-3
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How Dietary Fiber Supports Gut and Colon Health

Jun 19, 2026

“A meta-analysis of 25 prospective studies associated each additional 10 grams of daily fiber with about a 10 percent lower risk of colorectal cancer, with especially consistent findings for cereal fiber and whole grains.”

nutrition cancer gut immune system
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How Exercise and Sleep Support Immune Function With Age

Oct 29, 2025

“A systematic review in older adults linked Mediterranean dietary patterns with lower inflammatory markers, while a meta-analysis of randomized trials found that vitamin D supplementation reduced acute respiratory infection risk overall, with the strongest protection among people who were very deficient and received regular doses.”

nutrition exercise aging sleep
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How Exercise Intensity Relates to Longevity

Jul 29, 2026

“During about eight years of follow-up, the models associated one vigorous minute with roughly 4.1 moderate minutes for all-cause mortality, 7.8 minutes for cardiovascular mortality, and 9.4 minutes for type 2 diabetes risk.”

exercise obesity diabetes muscle
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How Lactate Links Vigorous Exercise to Brain Health

Jan 7, 2026

“In 15 people with severe traumatic brain injury, sodium lactate infusion increased brain lactate, pyruvate, and glucose without raising intracranial pressure, and a randomized study in 60 patients with mild traumatic brain injury reported better cognitive recovery than hypertonic saline.”

exercise brain mitochondria rhonda
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How Magnesium Supports DNA Repair and Healthy Aging

Sep 1, 2025

“Other cohorts have produced less consistent cancer findings, so the strongest practical message is to meet magnesium needs through foods such as leafy greens, legumes, nuts, seeds, and whole grains, with supplements individualized for diet, kidney function, and medications.”

cancer aging dna damage micronutrients
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How Much Protein Maximizes Muscle Gains

Nov 6, 2025

“A meta-analysis of 49 studies involving 1,863 adults found that protein supplementation during prolonged resistance training produced additional gains in one-repetition maximum strength, fat-free mass, and muscle size compared with training alone.”

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How Multivitamins and Sulforaphane Support Healthy Aging

Nov 14, 2025

“Sulforaphane activates NRF2-regulated cellular defense pathways. In a randomized crossover trial of 60 adults, eating 85 grams of raw watercress daily for eight weeks reduced basal lymphocyte DNA damage by 17% and oxidative purine DNA damage by 23.9%.”

cancer micronutrients rhonda sulforaphane
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How Nicotinamide Riboside Relates to Exercise Recovery

Feb 25, 2026

“In eight young men, seven days of 1,000 milligrams of NR per day changed selected muscle NAD metabolites but did not alter substrate use, mitochondrial respiration, or signaling involved in adaptation to one hour of endurance exercise.”

exercise aging metabolism inflammation
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How Omega-3, Vitamin D, and Exercise Affected Aging Clocks

Jun 10, 2026

“In a randomized factorial design, participants were assigned to one gram per day of algae-derived omega-3 or placebo, 2,000 IU of vitamin D3 or placebo, and a 30-minute home strength program three times weekly or a flexibility control.”

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