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FoundMyFitness library

Related Episodes for Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration: Can We Change the Pace?

Ranked by shared topics, with one result from each original episode.

81
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Aliquot #87: Advanced glycation end-products (AGEs) – byproducts of glucose metabolism that promote aging

Apr 29, 2023

“Advanced glycation end-products, or AGEs for short, are created when the sugars, amino acids, and fats in food encounter heat. AGEs also form in the body during normal glucose metabolism. However, if high levels of AGEs accumulate in the tissues and blood, they can become pathogenic.”

aliquot diet aging metabolism
Duration: 19m 19s
82
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Aliquot #9: Sulforaphane: Discovery, research, and health effects

Nov 5, 2020

“Sulforaphane switches on mechanisms that protect against cancer and other environmental insults. Sulforaphane is produced when the plants' cells are damaged by chewin or chopping and some culinary "hacks" favor its production.”

aliquot cancer environment sulforaphane
Duration: 36m 12s
83
Aliquot Premium

Aliquot #90: Inflammation and the Early Seeds of Dementia — and Its Prevention

Jun 4, 2023

“Preventing dementia requires a lifelong and multipronged approach that involves keeping inflammation (and its aging effects) at bay and making healthy lifestyle choices, such as exercising and consuming omega-3 fatty acids.”

aliquot exercise brain aging
Duration: 21m 40s
84
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Aliquot #91: How blood-brain barrier dysfunction fuels Alzheimer's disease

Jun 29, 2023

“Genetic predisposition, altered glucose uptake in the brain, high blood pressure, and other factors can weaken the barrier's integrity, allowing endotoxins and inflammatory immune cells to infiltrate the brain and increasing a person's risk for dementia.”

aliquot brain alzheimer's inflammation
Duration: 36m 13s
85
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Aliquot #94: Why Sulforaphane Matters: The Science of Cellular Protection

Aug 27, 2023

“Sulforaphane, a bioactive compound derived from broccoli, broccoli sprouts, and red kale, exerts potent antioxidant and anti-inflammatory properties that can combat various chronic and acute diseases.”

aliquot inflammation sulforaphane antioxidant
Duration: 27m 15s
86
Aliquot Premium

Aliquot #96: Thermal Stress, Part I: The Science Behind Heat Stress and its Positive Effects on Health

Oct 22, 2023

Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...

aliquot aging metabolism heat stress
Duration: 43m
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Accelerating Alzheimer's detection with biomarkers | Axel Montagne, Ph.D.

Mar 25, 2023

“Early biomarkers of vascular dysfunction, such as soluble platelet-derived growth factor receptor-beta (sPDGFR-β), can help identify individuals at risk for developing Alzheimer's disease. These biomarkers are being validated on high-throughput platforms for large-scale testing.”

brain alzheimer's aging
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88
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Does animal research help us understand human aging? │ Dr. George Church

Sep 2, 2022

“However, the ability to translate data from non-human animals to humans can be limited and the use of laboratory animals can raise ethical concerns. In this clip, Dr. George Church describes the pros and cons of animal research and how we could move beyond its use with advanced technologies.”

genetic engineering technology aging
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89
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Anti-cancer effects of ketones | Dominic D'Agostino

May 26, 2020

“Researchers in Dr. D'Agostino's laboratory observed a decreased tumor burden and enhanced survival in animals that were provided a ketone supplement, even if they were fed a high-carbohydrate diet.”

ketosis cancer
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90
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Anti-catabolic effects of heat | Dr. Stuart Phillips

Jul 10, 2022

“The mechanisms that drive the effects of sauna bathing include activation of heat shock proteins and pro- and anti-inflammatory cytokines; decreased blood pressure and arterial stiffness; and multiple improvements in cardiovascular function.”

muscle exercise aging heat stress
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