Related Episodes for MTHFR gene and supplementation with 5-L-methylfolate | Tim Ferriss

“Human trials suggest that alpha-lipoic acid can modestly improve selected lipid measures. A dose-response meta-analysis of 12 studies found reductions in total cholesterol, LDL cholesterol, and triglycerides across doses from 300 to 1,200 milligrams per day.”

“But evidence suggests that supplemental vitamin D in lactating women can increase breast milk concentrations to levels that are adequate to reduce the risk of deficiency in breastfed infants. In this clip, Dr. Rhonda Patrick describes the data suggesting that maternal supplemental vitamin D can reduce the risk of deficiency in breastfed infants.”

“Similarly, the timing of eating and exercise, especially in elite athletes, has not been studied and may, in fact, require self-experimentation by the athletes as they find the perfect interval of fasting to support their optimal performance.”

“In this video, Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles.”

“The pivotal role fiber plays in fueling good bacteria in the gut that act like "miniature drug factories" which produce compounds that regulate the immune system by increasing the number of T regulatory cells, which are specialized types of immune cells that keep the immune system in check and prevent autoimmune responses.”

“Robust scientific evidence indicates that consuming a plant-rich diet that provides vitamins, minerals, fiber, and phytochemicals is healthier than consuming an all-meat diet. In this clip, Dr. Jed Fahey rebuts popular claims that an all-meat diet is healthful.”

“The menus were matched for presented calories, energy density, total sugar, sodium, and fiber, but not added sugar: much more of the ultra-processed diet's sugar was added rather than contained in fruit. Protein was also only approximately matched, at about 14% versus 15.6% of calories.”

“In a short intervention in 29 healthy young men, a daily sugar-sweetened beverage increased fasting glucose, C-reactive protein, and atherogenic LDL features within three weeks; this was a biomarker study, not a cancer trial.”

“A national survey analysis estimated 2.6% severe deficiency, 22% moderate deficiency, and 40.9% insufficiency among US adults, although prevalence changes with the threshold used. These categories should remain distinct because insufficiency is not the same as clinical deficiency.”

“A 12-month randomized controlled trial found that vitamin D supplementation improved cognitive function, intelligence quotient scores, telomere length, and lowered oxidative stress markers in older adults with mild cognitive impairment (compared to placebo), suggesting that not only does vitamin D supplementation improve biomarkers of aging, but also functional outcomes.”