Related Episodes for Sleeping pills correlated with increased cancer risk and decreased brain plasticity | Matthew Walker

“Migraine is a neurological disorder that typically manifests as an intense, debilitating headache and is often accompanied by nausea, vomiting, and light sensitivity. Roughly 15 percent of people worldwide experience migraines, with women reporting them more often than men.”

“When it comes to managing inflammation, we often focus on what lifestyle habits we might need to get rid of, but it's just as important to focus on things we can add to our lifestyles. In this Aliquot, we'll talk about my top recommendations for lifestyle habits that reduce inflammation.”

“Vascular dysfunction, the loss of normal endothelial tone and permeability of blood vessels, is a common feature of most forms of dementia, including Alzheimer's disease. People who carry the APOE4 gene are at greater risk for vascular dysfunction and Alzheimer's disease.”

“Sulforaphane switches on mechanisms that protect against cancer and other environmental insults. Sulforaphane is produced when the plants' cells are damaged by chewin or chopping and some culinary "hacks" favor its production.”

“Preventing dementia requires a lifelong and multipronged approach that involves keeping inflammation (and its aging effects) at bay and making healthy lifestyle choices, such as exercising and consuming omega-3 fatty acids.”

“Genetic predisposition, altered glucose uptake in the brain, high blood pressure, and other factors can weaken the barrier's integrity, allowing endotoxins and inflammatory immune cells to infiltrate the brain and increasing a person's risk for dementia.”

“A four-week pilot study in people with type 2 diabetes reported improved insulin-stimulated glucose disposal after oral alpha-lipoic acid, while a three-week randomized trial found that intravenous 600 milligrams per day reduced diabetic neuropathy symptoms.”

“Animal studies indicate that omega-3 deficiency may also reduce GLUT1 transporters in the brain. Other studies suggest that omega-3 supplementation reduces VCAM1 levels – a protein elevated with normal aging, which could be related to the breakdown of the blood-brain barrier.”

“Researchers in Dr. D'Agostino's laboratory observed a decreased tumor burden and enhanced survival in animals that were provided a ketone supplement, even if they were fed a high-carbohydrate diet.”

“Approximately 25 percent of people living in the United States carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”