Related Episodes for The effect of sauna on depression and mood | Rhonda Patrick

“Sleep and the immune system are intrinsically linked. Sleep problems may arise because of medical or behavioral reasons, but modern life frequently dictates a work schedule late into the evening, disrupting our natural sleep/wake cycles.”

“When most people think about certain lifestyle factors that affect insulin sensitivity and blood glucose levels, they think about macronutrient composition, or calories, or fasting, or exercise (and lack of), but they don’t often think about sleep.”

“In a placebo-controlled study of eight healthy adults, adrenaline infusion lowered plasma magnesium, and levels had not recovered one hour later. Investigators proposed a shift into cells after beta-adrenergic stimulation; the study did not measure cortisol, urinary loss, total-body depletion, or clinical deficiency.”

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”

“Inflammation is a critical element of the body’s immune response. Chronic inflammation, which occurs on the cellular level in response to toxins or other stressors, plays a key role in the development of many diseases, including depression.”

“Protein before or after exercise can support adaptation, while total daily intake matters most. Third, distribute protein across three or four meals, with older adults often needing 20–30 grams or more per meal, while there is no small hard ceiling.”

“A systematic review and meta-analysis found no evidence that one time of day produces universally better improvements in health or performance, although gains can be larger when the time of training matches the time of testing.”

“Time-restricted eating, which involves taking in food within a specific period of the day and fasting for the remainder, can improve certain biomarkers of health - even without weight loss. One theory is that this eating pattern coordinates food intake with the body's peak metabolism period.”

“Since then, countless studies have tested Pauling's theories about vitamin C, colds, and cancer (and many others), and a substantial body of evidence has emerged, identifying critical roles for vitamin C in immune function, cardiovascular and respiratory health, cognitive development and preservation, and many other aspects of human health.”

“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”