Search results for cholesterol

Explore LDL and HDL particle size, diet, statins, and heart disease through study summaries and expert discussions with Rhonda Patrick.

“Even though small dense particles carry less cholesterol, they are more apt to deposit in the artery wall and become oxidized, thus leading to artery damage. In this clip, Dr. Ronald Krauss discusses that in clinical practice, cholesterol particle size may be more relevant than the amount of cholesterol.”

“Evolocumab lowered LDL by 59% and reduced the primary composite cardiovascular outcome over a median 2.2 years. Bempedoic acid is activated in the liver, where it inhibits cholesterol synthesis and promotes increased LDL receptor activity.”

“Cholesterol is vital to human health, but an oversimplified view of cholesterol — that high-density lipoprotein (HDL) cholesterol is good, and low-density lipoprotein (LDL) cholesterol is bad — has led to a gross misunderstanding of the nuances that define the differences in cholesterol-containing lipoproteins.”

“An American Heart Association science advisory likewise emphasizes the overall dietary pattern and notes that intervention studies can show small increases in total or LDL cholesterol as dietary cholesterol rises. Observational cardiovascular findings conflict.”

“Coffee contains the diterpenes cafestol and kahweol, which can raise circulating cholesterol when they remain in the final drink. Paper filters retain much of these compounds, while boiled coffee, French press, and other unfiltered methods leave more behind.”

“Where we get into trouble is when it exceeds the ability of cells to take cholesterol out of the blood quickly through the liver." - Ronald Krauss, M.D. Cholesterol is vital to human health, and every cell in the body is capable of producing its own.”

“Most of the cholesterol in our body is made by the body itself and minimally influenced by the cholesterol we eat. The recommendation to limit dietary cholesterol to less than 300 milligrams per a day was not backed by quality research and is no longer recommended.”

“Statins can reduce the risk of heart disease by 30 to 40 percent due to their ability to increase LDL receptor activity and reduce blood cholesterol levels. Whether the drugs are overprescribed (or perhaps under-prescribed) is a matter of great debate.”

“In this clip from Q&A #78, Dr. Rhonda Patrick discusses supplements that can complement diet, exercise, and clinician-guided treatment for high cholesterol. Viscous soluble fiber has some of the strongest evidence.”