Search results for serotonin

“Another randomized study found better long-term picture-location memory when exercise occurred four hours after learning, showing that timing can shape the result. Dr. Patrick also discusses serotonin and hippocampal neurogenesis as a possible biological link.”

“Managing depressive symptoms Selective serotonin reuptake inhibitors (SSRIs) in conjunction with cognitive behavioral therapy are typically the first line of treatment for people who have depression.”

“Chemically, psilocybin is rapidly metabolized into psilocin, which acts as a serotonin 2A receptor agonist, producing profound alterations in consciousness. In clinical settings, psilocybin is administered as a synthesized compound under tightly controlled conditions, involving extensive participant preparation and professional support to ensure safety and maximize therapeutic outcomes.”

“BDNF reduces appetite and alters behavior in animals "Mice lacking the serotonin-producing gene have higher BDNF levels in the hippocampus and prefrontal cortex.". Several studies have shown that BDNF signaling reduces appetite in animals.”

“Reduced inflammation driven by IL-6 also positively impacts the kynurenine pathway by limiting the diversion of tryptophan away from serotonin production. Lower levels of BDNF are frequently observed in depression, with depressed individuals often displaying BDNF concentrations 10–20% lower than healthy counterparts.”

“Alcohol causes serotonin release in the median and dorsal raphe, which are involved in impulses, motivation and reward, and stress and anxiety responses. Initially, this serotonin contributes to the "feel good" sensations some people experience when drinking.”

“Magnesium also enhances the activity of serotonin N-acetyltransferase, an enzyme required for melatonin synthesis, potentially improving sleep. Interestingly, sleep deprivation markedly depletes magnesium levels, but whether these alterations create a vicious cycle of sleep impairments is unclear.”

“Drugs that modulate neurotransmitter (e.g., serotonin, dopamine, acetylcholine) concentrations are a common strategy for treating alcohol misuse and neuropsychiatric disorders; however, many patients don't adequately respond to these drugs.”

“They also showed that serotonin depletion impairs vagal nerve activity, in turn reducing hippocampal activity and driving neurocognitive dysfunction. Giving the mice a selective serotonin reuptake inhibitor (SSRI, a drug that promotes serotonin uptake in the gut) improved their cognitive function.”