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“Adding a sugar-sweetened beverage to a protein-rich meal decreased fat use and diet-induced thermogenesis by more than 40% in people. The study involved participants that spent 24 hours in a metabolic chamber on two separate occasions.”

“Interestingly, the beneficial effects of a high fat diet were only observed with the ketogenic diet. Feeding the mice a high-fat, high-carbohydrate diet or providing exogenous ketones in the diet had no beneficial effects against influenza virus.”

“However, it's important to mention that BMI is a limited measure because it doesn't distinguish between fat and lean mass and can therefore miss meaningful shifts in fat distribution. The gut microbiome continued to show donor traits, which might help explain the observed health effects.”

“It also increased the use of intramuscular triglycerides over glycogen in muscle tissue. Exercise while fasted also caused mitochondria to increase gene activity in genes related to fatty acid metabolism making them more efficient as using fat for energy.”

“Researchers also found that the diabetic drug rosiglitazone (lowers blood sugar) also increases fat accumulation inside bone. Exercise reverses this.”

“These reductions in semen quality were more pronounced among the men with the highest BMIs. Men with overweight had lower semen volume and motility than healthy-weight men. These findings suggest that excess body fat reduces semen quality, potentially contributing to infertility.”

“People with higher than normal levels of visceral fat also had significantly higher levels of these pieces of DNA and this also associated with insulin resistance. Here is a press release for the study: http://medicalxpress.com/news/2016-03-results-cell-free-dna-involved-inflammation.html”

“Researchers found that a glucocorticoid receptor in fat tissue can affect the way the brain controls stress and metabolism. Initially, such signals from the receptor can be lifesavers, directing the brain to regulate its energy balance and influencing stress responses in a beneficial way.”

“FTA: > New research suggests that signs of brain aging can be postponed in mice if placed on a high-fat diet. In the long term, this opens the possibility of treatment of children suffering from premature aging and patients with Alzheimer's and Parkinson's disease.”

“A diet low in refined sugar improved fat and inflammation in the livers of boys with nonalcoholic fatty liver disease. They reduced their fatty liver disease from 25% to 17% while the boys with their standard diet had a reduction from 21% to 20%.”