Search results for aging

Dr. Rhonda Patrick discusses child nutrition, osteoporosis, cholesterol-lowering supplements, her skincare routine, and fasting versus prioritizing protein.

“Accelerated aging syndromes, such as Werner syndrome and Hutchinson-Gilford progeria syndrome, are characterized by genetic mutations that promote increased DNA damage, particularly at telomeres.”

“A growing body of evidence, however, suggests that a ketogenic diet, which is low in carbohydrates and rich in protein, fiber, and healthy fats, contributes to overall health and may be beneficial in preventing many chronic diseases, including Alzheimer's disease.”

“A healthy immune system allows the body to fight bacterial and viral infections, as well as aberrant cells, which, left unchecked can progress to cancer. Insulin-like growth factor 1 (IGF-1) has some beneficial functions but is also known to promote the growth of existing cancer cells.”

“01:17:51 - What gene therapy costs and how scaling this technology may make it affordable for everyone. 01:19:39 - How mRNA vaccine technology may be applied to counter immunosenescence – the exhaustion of the aging immune system.”

“He directs the USC Longevity Institute as well as the Oncology and Longevity Program at the Institute of Molecular Oncology Foundation in Milan, Italy. His research centers on understanding the fundamental genetic and biochemical mechanisms of aging in yeast, mice, and humans.”

“Dr. Patrick places creatine within healthy aging because resistance training and adequate nutrition counter the loss of muscle, strength, and bone associated with sedentary aging. She also mentions emerging brain research without treating it as established proof for every cognitive outcome.”

“By studying aging pathways, scientists have recognized that maintaining efficient mitochondria is a fundamental approach to staying young. In animal studies, the mitochondrial enzyme nicotinamide riboside, when provided as a supplement, protected the animals against age- or noise-induced hearing loss.”

“Aging contributes to neuroinflammation, causing endothelial cells to adopt a pro-inflammatory phenotype, which is thought to ultimately drive the detachment of pericytes and contribute to the breakdown of the blood-brain barrier and the pathophysiology of various dementias, including Alzheimer's disease.”

“In humans, a naturally occurring IGF-1 deficient population exists in a region of Ecuador. These individuals live slightly longer and do not succumb to the diseases of aging compared to their relatives with typical IGF-1 receptors, regardless of diet and lifestyle practices.”