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“Chloroquine and hydroxychloroquine are antimalarial drugs currently being used under Emergency Use Authorization as treatments for COVID-19. Recently published data from a mouse study suggest that these drugs carry a significant risk of death when either is given in combination with metformin.”

“However, roughly 30 percent of people taking the drugs are resistant to their effects. A recent systematic review and meta-analysis found that people with depressive symptoms who took psilocybin were two times more likely to respond to treatment than those not taking the drug.”

“The drugs studied were psilocybin, lysergic acid diethylamide (LSD), mescaline, N,N-dimethyltryptamine (DMT), and ayahuasca. Across these drugs, the clearest overall pattern was that certain groups of brain areas that usually work more independently became more connected.”

“They found that people who used GLP-1 receptor agonists were more than twice as likely to develop neovascular age-related macular degeneration than those who didn't use the drugs. About 0.2% (93) of the users developed the condition, compared to 0.1% (88) of non-users.”

“Patients with melanoma who received immunotherapy drugs were 65% less likely to develop colitis if they also supplemented with vitamin D. These findings were validated in another group of 169 patients, which found that vitamin D supplementation lowered the chances of developing colitis by 54%.”

“The biology of aging is increasingly seen as treatable, and drugs like semaglutide—once solely used for diabetes and weight loss—may be part of the solution. A recent study found that people with HIV who took semaglutide for 32 weeks experienced up to a 4.9-year reduction in biological age, as measured by changes in DNA methylation.”

“Some NSAIDs dampen inflammation by switching on the activity of Nrf2. Non-steroidal anti-inflammatory drugs, or NSAIDs, are among the most widely used drugs worldwide, available in both prescription and over-the-counter forms.”

“From the article: > Lee and his colleagues tested 880 bioactive substances – including drugs and vitamins – approved by the U.S. Food and Drug Administration (FDA) to see if they stimulated the mouse stem cells to become heart muscle cells.”

“Robust data from randomized controlled trials point to the effectiveness of regular vigorous exercise in reducing high blood pressure, potentially offering a drug-free approach to managing the condition. Adequate protein intake is essential for preserving lean muscle mass, especially as we age.”

“Also very interesting: > The Salford team also identified eight other drugs that could be used as a "second-punch" after the antibiotic regime, including berberine (a natural product) -- and a number of cheap non-toxic FDA approved drugs.”