Search results for heat stress

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Dysregulation of glucocorticoid receptors promotes inflammation, a driver of many diseases. During periods of intense psychosocial stress, glucocorticoid receptors increase in the brain, but mineralocorticoid receptors decrease.”

“Evidence depends on the protocol, population, and outcome, and acute cold can itself trigger a stress response. The practical takeaway is to prioritize a sustainable diet and regular exercise, then treat heat, meal timing, or cold as optional context-dependent tools.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick discusses supplement timing, exercise timing, supplements in older adults, folic acid vs. folate, and hydrogen-rich water.

“Nearly half of all adults in the United States have high blood pressure, defined as having a systolic pressure of 130 mmHg or higher or a diastolic pressure of 80 mmHg or higher. Maintaining early healthy blood pressure is critical to ensuring the proper functioning of blood vessels in the brain and blood-brain barrier integrity.”

Dr. Rhonda Patrick discusses silicone safety, grounding, pentadecanoic acid, and the potential benefits of olive leaf extract and peptides.

“In this clip, Dr. Dominic D'Agostino explains the interrelationship between ketones and lactate as sources of energy for the brain and the role ketones may have in reducing oxidative stress through greater energetic efficiency.”

“IGF-1 activates the AKT pathway which, in part, inhibits the FOXO pathway -- an important transcription factor. When FOXO is NOT inhibited it activates genes which help with stress resistance, anti-oxidant genes, genes involved in DNA repair, genes involved in degrading bad proteins.”

“A May 2025 Nature paper showed taurine uptake may fuel aggressive myeloid leukemias in laboratory and mouse models, illustrating how nutrients beneficial to healthy tissues may also feed certain cancers.”