Search results for Exogenous ketones

“Ketones provide benefits that extend beyond the brain, however. For example, beta-hydroxybutyrate, an endogenous ketone, may reduce inflammation, increase lifespan, and suppress tumor formation. Learn more about beta-hydroxybutyrate in our overview article.”

“In this 45-minute podcast, Dr. Patrick answers some of the most popular questions related to fasting, including: What effects coffee, supplements, and amino acids have on fasting. Whether one method of fasting is more beneficial than others. What effect the consumption of exogenous ketones have on fasting.”

“Ketone esters are exogenous ketone bodies that may promote ketosis in humans. Animal models demonstrate that ketone esters exert beneficial effects in Alzheimer's disease, effectively reducing amyloid accumulation, neurofibrillary tangles, and tau, while improving learning and memory.”

“Ketone signaling also depends on metabolic context. Dr. Bikman describes low glucose together with elevated endogenous ketones as a coordinated fasting-like signal; low glucose without a meaningful ketone rise is not the same physiological state.”

“Dom's efforts at teasing out the differences between induced nutritional ketosis (through a low carbohydrate, high fat diet) and ketosis from the dietary introduction of exogenous ketones, like beta-hydroxybutyrate, especially in the context of therapeutic and performance enhancing effects.”

“He further details how he combines the ketogenic diet, exogenous ketones, intermittent fasting, and exercise into his daily life. In this clip, Dr. Dominic D'Agostino gives his thoughts on eating an all-meat diet and weighs in on whether it is optimal to eat a diet devoid of fiber.”

“How this inhibition of class 1 HDACs leads to the increased expression of notorious longevity gene Foxo3, which may help explain why mice given an exogenous beta-hydroxybutyrate ester had lower markers of inflammation and oxidative damage, which are physiological contributors to the aging process.”

“Although this was a small study, these findings suggest that exogenous ketone supplementation impairs performance in endurance athletes in a setting of short-duration, high-intensity training.”

“A recent cell study found that beta-hydroxybutyrate, a type of ketone, helps protect the brain by targeting toxic proteins for disposal. Researchers delivered beta-hydroxybutyrate to brain cells collected from mice and monkeys via an exogenous ketone ester.”

“Interestingly, the beneficial effects of a high fat diet were only observed with the ketogenic diet. Feeding the mice a high-fat, high-carbohydrate diet or providing exogenous ketones in the diet had no beneficial effects against influenza virus.”