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“When produced during exercise (especially high intensity workouts like cycling, which shifts metabolism toward glycolysis to more quickly meet the high energetic demands), lactate switches on more than 600 genes involved in muscle adaptation, stimulates mitochondrial biogenesis – the process of making new mitochondria – and promotes protein synthesis, which is essential for muscle growth.”

“Refined and starchy carbohydrate excess can worsen insulin resistance and triglyceride-rich VLDL export; VLDL is a major precursor of LDL. Saturated fat can increase cholesterol synthesis and reduce hepatic LDL-receptor-mediated clearance, although individual responses vary greatly.”

“As for this last point in particular, but also all conversations surrounding severe life-altering diagnosis like cancer, these clips are not meant to serve as a substitute for medical advice.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Insulin-like growth factor 1 (IGF-1) plays a role during childhood for growth and continues later in life to have anabolic and neurotrophic effects. IGF-1 is also implicated in contributing to aging and enhancing the growth of cancer after it has been initiated.”

“Mitochondria are best known for their energy-producing roles, but they also help regulate cellular metabolism, signaling, and apoptosis (programmed cell death). As a result, mitochondrial health is intrinsically linked to overall health.”

“Time-restricted eating, in particular, has the potential to realign the body's circadian rhythms. In this clip, Dr. Rhonda Patrick describes some of the different types of fasting and identifies the advantages associated with each.”

“In this clip from the FoundMyFitness interview with Dr. Ben Bikman, he recommends changing breakfast after the overnight fast. His practical options are to delay the first meal or choose protein, healthy fats, fiber-rich plants, and minimally processed carbohydrates instead of refined starch and sugar.”

“Researchers believe incorporating these fatty acids into mitochondrial membranes might alter ADP handling and oxygen utilization, potentially affecting muscle protein synthesis and energy production.”