Search results for oxidative stress

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“01:16:35 - Rhonda mentions tumor suppressor genes, which are activated by hormesis (good stress triggered by things like isothiocyanates). 01:19:20 - Joe brings up Dave Asprey's take on boiling kale to remove oxalic acid.”

“Rather, they fall on a spectrum, ranging from a five-to-one ratio of fats to protein and carbs (typically used in clinical settings) to a more liberalized one-to-one ratio, a type of low glycemic index therapy (commonly referred to as "modified Atkins") that might meet the needs of most healthy people.”

“00:26:58 - The differences between macroautophagy, microautophagy, and chaperone-mediated autophagy. 00:28:03 - The difference between autophagy that is dictated by demand (nutrient stress) versus autophagy that occurs as the need arises to recycle damaged organelles.”

“The condition can be halted or reversed with dietary and lifestyle modifications, including weight loss, exercise, and stress reduction. But most people with prediabetes don't know they have the disorder until it has transitioned to diabetes.”

“Mitochondrial health and overall health are intrinsically linked. Identifying ways to boost mitochondrial biogenesis – the formation of new mitochondria – ensures that cells maintain an adequate number of mitochondria to meet their energy needs.”

“Dr. Patrick also discusses reductive stress: suppressing reactive oxygen species too strongly around training could blunt exercise signaling and adaptation. High-dose melatonin should therefore not be treated as a benign way to improve every exercise outcome.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Mitochondrial biogenesis, the formation of new mitochondria within cells, is boosted by exercise to meet heightened energy needs. While all forms of exercise can promote this process, high-intensity interval training (HIIT) might accelerate the surge in mitochondrial content more swiftly than continuous exercise.”