New gene-editing CRISPR technique successfully corrected mutations in the gene that causes Duchenne muscular dystrophy in heart muscle cells.
“The researchers found that correcting less than half of the heart muscle cells was enough to rescue cardiac function to near-normal levels in the heart tissue. Duchenne muscular dystrophy leads to degeneration of skeletal and heart muscles.”
Episode
Why AI Could Add Decades to Your Lifespan | Dr. Derya Unutmaz
“Jennifer Doudna, Ph.D. - Nobel Prize-winning biochemist and co-developer of CRISPR-Cas9, mentioned in connection with new genome-editing tools. Andrej Karpathy, Ph.D. - AI researcher referenced for a personal wiki/database workflow that can preserve long-term context for AI systems.”
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Curing the donor organ shortage with gene editing │ Dr. George Church
“Xenotransplantation, the practice of transplanting an organ from a non-human animal, such as a pig or chimpanzee, to a human, has its origins in the 1960s. Among six patients receiving kidney xenotransplants from chimpanzees in 1963, one survived for nine months in moderate health.”
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Discovery of genes that reset the Horvath Clock | David Sinclair
“Dr. Shinya Yamanaka discovered a group of proteins that can reprogram differentiated (mature) cells into pluripotent stem cells. These proteins, now called Yamanaka factors, are highly expressed in embryonic stem cells in mice and humans.”
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Bacteriophage cocktail therapy: a next generation tool for the microbiome | Dr. Eran Elinav
“Bacteriophage therapy, possibly using a cocktail of phages, could precisely perturb the microbiome, eliminating pathogenic species while leaving commensal species unscathed and circumventing antibiotic resistance.”
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Eating to extend healthspan: overnutrition vs undernutrition | Ray Cronise
“Studies of centenarians suggest that lower levels of inflammation are associated with longevity. Different types of fiber provide fuel to diverse species of bacteria in the gut, which then synthesize byproducts that regulate the inflammatory process.”
Q&A
Q&A #38: Protein for Muscle and Longevity—Plant Sources, mTOR, & Cancer
Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.
Results 21–30 of 38