Search results for stress

“Meditation, in particular, slows biological aging by slowing the shortening of telomeres. Studies by telomere experts Elizabeth Blackburn at UCSF and Elisa Epel show that meditation buffers the stress that shortens telomeres and activates the gene that encodes for telomerase.”

“They measured the animals' motor, digestive, and brain function compared to normal mice and Parkinson's disease mice fed a normal diet. The authors found that sesaminol enhanced Nrf2 activity and increased production of antioxidant enzymes in response to oxidative stress.”

“Nrf2 activates the transcription of cytoprotective proteins that protect against oxidative stress due to injury and inflammation. Sulforaphane, a compound derived from broccoli and broccoli sprouts, is the most potent naturally occurring inducer of Nrf2.”

“Under resting conditions, two phosphorous molecules tether BAG3 in place, keeping it inactive. However, the researchers found that when cells experienced mechanical stress, the phosphorous molecules released BAG3, activating it and allowing it to perform its chaperoning job.”

“This means that it is likely that excess refined sugar may also inhibit Foxo3 in humans but future experiments need to illuminate this. Foxo3 is a master regulator of hundreds of genes that are involved in stress resistance, autophagy, and stem cell production.”

“Aerobic exercise (120 minutes per week) significantly lengthened telomeres, a biomarker for healthy aging, in white blood cells after 24 weeks in previously inactive, highly stressed older adults (randomized controlled trial).”

“Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study. NAD+ in aging, metabolism, and neurodegeneration.”

“Because depression is often linked with less flexible stress regulation, a practice that repeatedly pairs physical effort, heat, breathing, and focused attention could plausibly help the body shift more effectively between strain and recovery.”

“Ashwagandha may help boost testosterone levels indirectly by reducing stress and lowering cortisol—a hormone that negatively impacts testosterone when elevated. Not all ashwagandha supplements are equal; effective versions are standardized to specific amounts of active compounds called withanolides.”

“It is well known that intense exercise induces oxidative stress and damage to your mitochondria, which dampens their ATP production (translation: lower oxidative capacity). But, your mitochondria have the ability to repair damage done to them using the same magnesium-dependent enzymes that I just mentioned.”