Search results for aging

“Since nicotinamide mononucleotide is found in a variety of food sources such as vegetables, fruits, and meat, future studies will focus on understanding whether it also prevents age-related physiological decline in humans.”

“Aging drives an array of physiological, functional, and mental changes in the human body. It is the primary risk factor for many chronic diseases in humans, including cancer, Alzheimer's disease, and cardiovascular disease.”

“Supplementing with 4,000 IU of vitamin D per day for 16 weeks reversed epigenetic aging by 1.85 years in overweight and obese African Americans that were low in vitamin D (randomized-placebo controlled trial). Epigenetic marks follow a certain pattern with age.”

“Vitamin C also improved how the mice stored and burned fat, decreased tissue inflammation and decreased oxidative stress in the WRN mice. From actual publication, rather than press release: > Daily ascorbate supplementation allowed [Werner mice] to recover a normal mean life span and healthy aging.”

“In dose–response analyses, the risk fell sharply as the ratio increased from low values and then leveled off once a moderate level was reached, with protective effects beginning around 0.9 in the U.S. and 1.06 in China, and little further benefit beyond those points.”

“Findings from a new study demonstrate that altering the gut microbial population may alter the aging process of the human brain. The authors of the study transplanted gut microbiota samples from healthy young or old mice into young germ­-free mice.”

“An antioxidant compound that is used in dye and has shown promise in treating Alzheimer's disease has now shown potential in reversing skin aging in human skin. The compound is called methylene blue and is a very potent antioxidant.”

“Telomeres are tiny caps on the end of our chromosomes that protect DNA from damage. Telomeres get shorter each year until they reach a critical length which causes the cell to either die or become senescent (metabolically inactive). When this occurs in stem cells, it leads to tissue aging.”

“[...] > The cyclists also did not increase their body fat or cholesterol levels with age and the men's testosterone levels also remained high, suggesting that they may have avoided most of the male menopause.”

“Even so, if controlled clinical trials confirm similar effects in people, these findings could point to a role for sulfur-containing compounds in supporting metabolic health and healthy aging. To learn more about how garlic affects metabolism, see Q&A #78, where I explore its effects on cholesterol levels.”