Search results for aging

“Protein misfolding in the brain is a central player in both aging and Alzheimer's disease, driving toxic protein buildup and brain cell dysfunction. However, evidence indicates that ketones—a critical brain fuel produced during fasting or exercise—may help reduce or prevent this damage.”

“Findings from a new study indicate that boys born to obese women perform poorly in measures of motor skills and intelligence compared to children born to healthy weight women. The study involved 368 children born to low-income African American or Dominican women living in the United States.”

“The participants who consumed the most fiber were 37 percent less likely to die from all causes of premature death than those who consumed the least, even when considering age, sex, body mass index, smoking, exercise, hypertension, diabetes, and abnormal blood lipids.”

“Aerobic exercise (120 minutes per week) significantly lengthened telomeres, a biomarker for healthy aging, in white blood cells after 24 weeks in previously inactive, highly stressed older adults (randomized controlled trial).”

“The levels of a protein called VCAM1 increase in blood with age and it was found that blocking the action of this protein did not lead to these negative effects when the old blood was transplanted into young mice.”

“When they applied the mechanical device to the skin, cerebrospinal outflow doubled, even in aged mice. These findings suggest that poor glymphatic waste clearance in aging may be reversible by stimulating functional lymphatic vessels in the face.”

“They also highlight how metabolic health in midlife can influence cognitive aging, especially for those with obesity. Poor sleep can suppress the effects of leptin, ultimately impairing metabolic function. Learn more in this clip featuring Dr. Matt Walker.”

“Aerobic exercise found to maintain brain volume in the left hippocampus in 14 different controlled trials suggesting aerobic exercise may prevent brain aging. The exercise protocols in the 14 trials ranged from walking to jogging to cycling.”

“As we'll learn from Judy, there's more than one so-called phenotype exhibited by senescent cells and they arrive at these different cellular phenotypes as a consequence of different types of cellular stress or dysfunction. Judy is a professor of biogerentology at the Buck Institute for Research on Aging and a co-editor in chief of the AGING Journal.”

“Human data associate circulating AGEs with aortic stiffness in hypertension, but this does not prove that short sleep caused the AGE burden or that lowering HbA1c reverses cardiac aging. Sleep loss also changes leptin, ghrelin, hunger, and preference for energy-dense foods.”