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Dr. Rhonda Patrick discusses nicotinamide riboside, biomarkers, belly fat loss, sex-specific health, curcumin & ashwagandha safety.

“In a small trial of 30 people with stable heart failure, 1,000 milligrams twice daily approximately doubled whole-blood NAD and appeared tolerable while supporting further study rather than proving treatment benefit.”

Dr. Rhonda Patrick explores blood tests to track health, statin alternatives, mitochondrial supplements, and vitamin B12 and autism risk in her latest Q&A.

“Rather, they fall on a spectrum, ranging from a five-to-one ratio of fats to protein and carbs (typically used in clinical settings) to a more liberalized one-to-one ratio, a type of low glycemic index therapy (commonly referred to as "modified Atkins") that might meet the needs of most healthy people.”

“Alterations in magnesium and oxidative status during chronic emotional stress - Young adults undergoing persistent or intermittent stress like anticipating military conflict) experienced substantial decreases in their overall and plasma magnesium concentrations over three months.”

“In 15 people with severe traumatic brain injury, sodium lactate infusion increased brain lactate, pyruvate, and glucose without raising intracranial pressure, and a randomized study in 60 patients with mild traumatic brain injury reported better cognitive recovery than hypertonic saline.”

Dr. Ruth Patterson discusses the role of fasting in the prevention and survivorship of breast cancer.

“Researchers have observed synergism between the ketogenic diet and hyperbaric oxygen against tumor cells. Moreover, Dr. D'Agostino suggests that ketosis stimulates the immune system, increasing its ability to detect cancer cells.”

“Obesity promotes inflammation and elevated levels of the hormones estrogen and insulin, which may lead to an increased risk of breast cancer. Acting as growth factors, both estrogen and insulin can promote tumor cell growth, as well as undermine the innate defense system that removes damaged cells from the body.”

“The body perceives these interventions as stressors and then adapts, ultimately developing metabolic flexibility. Dr. D'Agostino proposes that metabolic interventions, such as restricting calories and entering ketosis, for example, may provide additional benefits when practiced cyclically.”