Search results for brain

“Animals fed in this manner had enhanced cognition. Whether these effects will translate to humans remains to be seen. In this clip, Dr. Dominic D'Agostino describes animal research that explores the mechanisms by which the ketogenic diet may benefit the brain.”

“The brain makes some creatine locally and regulates entry from the blood through the blood-brain barrier. Dr. Candow therefore expects dose, duration, age, diet, and metabolic stress to influence how much supplemental creatine reaches brain tissue.”

“Dr. Rhonda Patrick examines how plastic-associated chemicals may influence neurodevelopment and how very small plastic particles may reach the brain. Preclinical studies suggest that BPA can alter estrogen signaling, neurotransmitter systems, and oxidative-stress pathways.”

“Potential mechanisms include improved brain bioenergetics, increased brain-derived neurotrophic factor (BDNF), and reduced neuroinflammation. Sleep deprivation: During situations of extreme sleep deprivation, a dose as high as 0.35 g/kg (25–30 grams of creatine) has been shown to improve memory, cognition, and brain creatine levels.”

“Glutathione helps prevent damage from oxidative stress caused by the production of reactive oxygen species that can occur after a traumatic brain injury. In this clip, Dr. Dominic D'Agostino discusses the neuroprotective potential associated with a combination of ketones and lactate in the management of traumatic brain injury.”

“Elevated levels of ketone bodies, such as beta-hydroxybutyrate, can have beneficial effects on several brain-related diseases. Research suggests that ketone bodies can increase blood flow in the brain by 30 to 40 percent, which may have profound effects for patients with brain injury or vascular dementia.”

“Creatine improved selected cognitive-task and brain-energy measures compared with placebo, providing an early signal that increased creatine availability may help the brain meet an acute energy challenge.”

“The use of alternate fuel sources allows glucose to be spared for the metabolic pathways that require it. In this clip, Dr. Dominic D'Agostino discusses the metabolic flexibility of the brain to use various substrates, including ketones, for energy.”

“Refined sugar also affects the brain. It impairs the brain’s ability to heal after trauma, inhibits memory formation and retention, and induces structural changes in the brain similar to those caused by amphetamine, cocaine, and nicotine – powerful stimulant drugs.”

“Inflammatory signaling can affect mood and cognition under strong experimental conditions. Intravenous endotoxin temporarily worsened mood in healthy volunteers, showing one pathway through which a substantial immune challenge can influence the brain.”