Search results for neurodegeneration

“Inflammation causes pericytes to release pro-inflammatory cytokines, compromising the barrier and facilitating neurodegeneration. Learn more about links between inflammation, pericytes, and cognitive decline in this clip featuring Dr. Axel Montagne.”

“The authors of the study posited that the mechanisms that drive this association may be related to inflammatory responses during a viral infection that could promote subsequent neurodegeneration, but they caution that their findings were observational and therefore not causal.”

“The two groups' biomarkers were similar at the beginning of the intervention, but YKL-40 and NfL increased slightly in the group that received the omega-3 fatty acid supplement, indicating a possible increase in neurodegeneration and inflammatory responses.”

“This exposure switched on the activity of brain microglia (immune cells); promoted the infiltration of pro-inflammatory immune cells and molecules into the brain tissues; and increased accumulation of amyloid-beta 42, a toxic protein associated with Alzheimer's disease and neurodegeneration.”

“Chronic brain inflammation is increasingly recognized as a contributor to neurodegeneration. Experimental studies also show that omega-3s influence processes such as the generation of new neurons and the stability and function of neuronal membranes.”

“This conversation with Dr. Charles Brenner is a deep dive into NAD biology—why it's foundational to energy metabolism, how it supports building and repair processes (including DNA repair), what actually seems to happen to NAD with aging, and how different stressors like obesity, inflammation, infection, circadian disruption, heart failure, and neurodegeneration can "attack" the NAD system.”

“These differences were associated with blood markers of glial activation and, to a lesser extent, neurodegeneration, as well as slower processing speed. Asthma has also been associated with approximately 20 to 33 percent greater odds of receiving a new Alzheimer's disease diagnosis over two years.”

“Yet cancer, metabolic disease, cardiovascular disease, and neurodegeneration can develop for years before diagnosis. AI may be especially valuable if it can identify a changing trajectory during this earlier window.”

“Over years, the repeated pattern of "intermittent hypoxia"—oxygen drops followed by reoxygenation—creates oxidative stress that may accelerate neurodegeneration. Severe, untreated OSA is now recognized as a risk factor for conditions like Alzheimer's disease.”

“When produced during exercise (especially high intensity workouts like cycling, which shifts metabolism toward glycolysis to more quickly meet the high energetic demands), lactate switches on more than 600 genes involved in muscle adaptation, stimulates mitochondrial biogenesis – the process of making new mitochondria – and promotes protein synthesis, which is essential for muscle growth.”